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Mini-Reviews in Medicinal Chemistry


ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Therapeutic Applications of Sugar-Mimicking Glycosidase Inhibitors

Author(s): Naoki Asano, Atsushi Kato and Alison A. Watson

Volume 1, Issue 2, 2001

Page: [145 - 154] Pages: 10

DOI: 10.2174/1389557013407052

Price: $65


Sugar-mimicking alkaloids inhibit the glycosidases involved in a wide range of important biological processes, principally owing to their structural resemblance to the sugar moiety of the natural substrate. The possibility of modifying and blocking these processes by using such inhibitors for therapeutic applications has attracted a lot of attention.

Keywords: Glycosidase Inhibitors, glycosidases, Castanospermine, Castanospermum australe, glucosidase inhibitors, Casuarina equisetifolia, Actinoplanes, antidiabetic agents, MANNOSIDASE INHIBITORS

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