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Mini-Reviews in Medicinal Chemistry


ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Pharmacological Strategies for Neuroprotection in Traumatic Brain Injury

Author(s): J. S. Jennings, A. M. Gerber and M. L. Vallano

Volume 8, Issue 7, 2008

Page: [689 - 701] Pages: 13

DOI: 10.2174/138955708784567377

Price: $65


Traumatic brain injury affects over a million Americans annually, but pharmacological therapy remains limited. Current standards of care in acute, subacute and chronic phases of injury are primarily supportive. This review discusses pharmacological strategies and future directions in patient treatment emphasizing pleiotropic agents targeting inflammation, oxidative damage, and glutamate excitotoxicity.

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