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Mini-Reviews in Medicinal Chemistry


ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Helicobacter Pylori, Zinc and Iron in Oxidative Stress-Induced Injury of Gastric Mucosa

Author(s): J. Dovhanj, K. Kljaic, K. Dodig-Curkovic, M. Curkovic, M. Volarevic and K. Marjanovic

Volume 9, Issue 1, 2009

Page: [26 - 30] Pages: 5

DOI: 10.2174/138955709787001767

Price: $65


A number of study have suggested a relationship between Helicobacter pylori infection and oxidative stress in the gastric epithelium. The oxidant- induced changes in zinc, iron, and vitamin C increase susceptibility to oxidative injury. Understanding of pathophysiologic mechanisms may provide new therapeutic strategies in treatment of oxidative injury of mucosa.

Keywords: Helicobacter pylori, zinc, iron, vitamin C, oxidative stress

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