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Mini-Reviews in Medicinal Chemistry


ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

New Potential Targets to Modulate Neutrophil Function in Inflammation

Author(s): R. A. Burgos, M. A. Hidalgo, C. D. Figueroa, I. Conejeros and J. L. Hancke

Volume 9, Issue 2, 2009

Page: [153 - 168] Pages: 16

DOI: 10.2174/138955709787316092

Price: $65


The importance of neutrophils in human disease such as rheumatoid arthritis, asthma, adult respiratory distress syndrome, and COPD has prompted the search for drugs capable to slow down neutrophil-dependent inflammation, without interference with innate immune responses. In this review, we summarize new potential drugs targets against neutrophils mediated inflammatory responses.

Keywords: Neutrophil, drugs, innate immunity, inflammation

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