Abstract
Chiral 3,4-difunctionalized pyrrolidines, which can be derived from L-(+)- and D-(-)-tartaric acids, are useful and versatile building blocks in total synthesis, catalyst preparation as well as supramolecular and medicinal chemistry. The preparation of these azacycles, possible transformations and their application are described herein.
Keywords: Tartaric Acids, C2-Symmetric Pyrrolidines, Chiral, Total Synthesis, Catalyst Design, Medicinal Chemistry
Current Organic Synthesis
Title: C2-Symmetric Pyrrolidines Derived from Tartaric Acids: Versatile Chiral Building Blocks for Total Synthesis, Catalyst Design, Supramolecular and Medicinal Chemistry
Volume: 6 Issue: 1
Author(s): Andreas Blum and Wibke E. Diederich
Affiliation:
Keywords: Tartaric Acids, C2-Symmetric Pyrrolidines, Chiral, Total Synthesis, Catalyst Design, Medicinal Chemistry
Abstract: Chiral 3,4-difunctionalized pyrrolidines, which can be derived from L-(+)- and D-(-)-tartaric acids, are useful and versatile building blocks in total synthesis, catalyst preparation as well as supramolecular and medicinal chemistry. The preparation of these azacycles, possible transformations and their application are described herein.
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Cite this article as:
Blum Andreas and Diederich E. Wibke, C2-Symmetric Pyrrolidines Derived from Tartaric Acids: Versatile Chiral Building Blocks for Total Synthesis, Catalyst Design, Supramolecular and Medicinal Chemistry, Current Organic Synthesis 2009; 6 (1) . https://dx.doi.org/10.2174/157017909787314902
DOI https://dx.doi.org/10.2174/157017909787314902 |
Print ISSN 1570-1794 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6271 |
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