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Mini-Reviews in Organic Chemistry


ISSN (Print): 1570-193X
ISSN (Online): 1875-6298

Recent Progress in the Synthesis of Naturally Occurring Triterpenoid Saponins

Author(s): Charles Gauthier, Jean Legault and Andre Pichette

Volume 6, Issue 4, 2009

Page: [321 - 344] Pages: 24

DOI: 10.2174/157019309789371541

Price: $65


This short review describes the recently reported semi- and total syntheses of naturally occurring triterpenoid saponins. Accent is placed on natural monodesmosidic and bidesmosidic saponins of the oleanane- and lupane-type that possess potent pharmacological properties including cytotoxic and antitumor activities.

Keywords: Natural products, Saponins, Triterpenes, Chemical synthesis, Cytotoxic, Anticancer

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