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Letters in Organic Chemistry


ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Demethylation of Aromatic Methyl Ethers Using Ionic Liquids under Microwave Irradiation

Author(s): Mikko Passiniemi, Mikko J. Myllymaki, Juha Vuokko and Ari M.P. Koskinen

Volume 8, Issue 1, 2011

Page: [48 - 52] Pages: 5

DOI: 10.2174/157017811794557741

Price: $65


An efficient demethylation reaction for aromatic methyl ethers has been developed. Deprotection reactions give high yields with butylpyridinium bromide under microwave irradiation. Basic and acidic functional groups are tolerated if the reaction is performed under acidic conditions.

Keywords: Aromatic ether, demethylation, ionic liquid, microwave irradiation, solvent free

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