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Current Drug Targets - Inflammation & Allergy

Editor-in-Chief

ISSN (Print): 1568-010X
ISSN (Online): 1568-010X

Neutrophils and Eosinophils: Clinical Implications of their Appearance, Presence and Disappearance in Asthma and COPD

Author(s): A. P. Watt, B. C. Schock and M. Ennis

Volume 4, Issue 4, 2005

Page: [415 - 423] Pages: 9

DOI: 10.2174/1568010054526313

Price: $65

Abstract

Asthma and chronic obstructive pulmonary disease (COPD) are common chronic disorders. Traditionally, asthma has been associated with an eosinophilic inflammation and COPD with neutrophilic inflammation. In this review we will highlight the maturation, recruitment, activation, action and apoptosis of these cells. In addition we will focus on the evidence for their presence in disease and suggest potential new therapeutic interventions.

Keywords: asthma, copd, eosinophils, neutrophils


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