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Recent Patents on Endocrine, Metabolic & Immune Drug Discovery

Editor-in-Chief

ISSN (Print): 1872-2148
ISSN (Online): 2212-3334

Obesity and Asthma

Author(s): Hans-Peter Hauber and Michael Wegmann

Volume 3, Issue 3, 2009

Page: [162 - 172] Pages: 11

DOI: 10.2174/187221409789104773

Price: $65

Abstract

Prevalence of obesity and bronchial asthma is increasing in industrialized countries. Several studies have suggested a relationship between these disorders. Evidence comes from studies with animal models as well as epidemiologic observations. Moreover, pulmonary function parameters, genetic and hormonal factors support the hypothesis that obesity and asthma are linked. Given the enormous economic impact effective and efficient treatment strategies for both diseases are important. The present review will describe patents and recent developments in drugs directed against obesity and asthma. Potential therapeutic targets include the ORL-1 receptor, the LPA receptor, the VEGF receptor, cannaboid receptor, T cells, and protein kinases.

Keywords: Asthma, cannaboid receptor, LPA receptor, obesity, ORL-1 receptor, protein kinase, T cell, VEGF receptor


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