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Current HIV Research


ISSN (Print): 1570-162X
ISSN (Online): 1873-4251

Letter to the Editor [HIV Drug Resistance on HAART Despite an Undetectable Viral Load]

Author(s): Pierre Loulergue, Constance Delaugerre, Vincent Jullien and Jean-Paul Viard

Volume 9, Issue 8, 2011

Page: [623 - 624] Pages: 2

DOI: 10.2174/157016211798998817


HIV is known to have the ability to adapt rapidly its genome under drug pressure, resulting in clinical treatment failure. We present the case of an HIV-infected patient who developed mutations of resistance to nevirapine although he always had an undetectable viral load and without context of inobservance. The concepts of undetectability and virological success in HIV infection must be balanced by the possible appearance of resistance under a treatment considered as effective.

Keywords: HIV, drug resistance, nevirapine, viral load, HAART, virological efficacy, threshold, saquinavir, immunovirologic treatment, plasma HIV RNA

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