Abstract
Magnetic resonance diffusion tensor imaging is a topic of active research, and is in constant development. Though state-of-the-art methods may not be practical for routine clinical use, small numbers of directional motionprobing gradients and relatively simple post-processing methods can yield clinically important information. Here we discuss the use of routinely acquired six-direction DTI of the brain at 3T to retrospectively study pathologies of the pediatric visual system. We discuss the use of DTI to investigate the effects of suprasellar tumors on pre-chiasmatic and chiasmatic optic nerves, and to diagnose and monitor septo-optic dysplasia and neurofibromatosis type 1. DTI can serve as a tool in surgical planning and pre-biopsy differential diagnosis. In congenital disease involving the white matter, DTI may prove useful in the diagnosis and monitoring of these conditions as they impact the pediatric visual system.
Keywords: Diffusion tensor imaging, tractography, pediatric visual system, septo optic dysplasia, neurofibromatosis
Current Pediatric Reviews
Title:Magnetic Resonance Diffusion Tensor Imaging and Diffusion Tensor Tractography in the Evaluation of Congenital and Acquired Diseases of the Pediatric Visual System
Volume: 8 Issue: 3
Author(s): Christopher G. Filippi and Keith A. Cauley
Affiliation:
Keywords: Diffusion tensor imaging, tractography, pediatric visual system, septo optic dysplasia, neurofibromatosis
Abstract: Magnetic resonance diffusion tensor imaging is a topic of active research, and is in constant development. Though state-of-the-art methods may not be practical for routine clinical use, small numbers of directional motionprobing gradients and relatively simple post-processing methods can yield clinically important information. Here we discuss the use of routinely acquired six-direction DTI of the brain at 3T to retrospectively study pathologies of the pediatric visual system. We discuss the use of DTI to investigate the effects of suprasellar tumors on pre-chiasmatic and chiasmatic optic nerves, and to diagnose and monitor septo-optic dysplasia and neurofibromatosis type 1. DTI can serve as a tool in surgical planning and pre-biopsy differential diagnosis. In congenital disease involving the white matter, DTI may prove useful in the diagnosis and monitoring of these conditions as they impact the pediatric visual system.
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Cite this article as:
G. Filippi Christopher and A. Cauley Keith, Magnetic Resonance Diffusion Tensor Imaging and Diffusion Tensor Tractography in the Evaluation of Congenital and Acquired Diseases of the Pediatric Visual System, Current Pediatric Reviews 2012; 8 (3) . https://dx.doi.org/10.2174/157339612802139406
DOI https://dx.doi.org/10.2174/157339612802139406 |
Print ISSN 1573-3963 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6336 |
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