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Current Medicinal Chemistry


ISSN (Print): 0929-8673
ISSN (Online): 1875-533X

Dendrimers in Photodynamic Therapy

Author(s): B. Klajnert, M. Rozanek and M. Bryszewska

Volume 19, Issue 29, 2012

Page: [4903 - 4912] Pages: 10

DOI: 10.2174/0929867311209024903

Price: $65


Photodynamic therapy (PDT) is a promising approach to treat certain types of cancer. PDT was proposed as a useful oncology tool more than 30 years ago but it has limitations. The success of PDT depends predominantly on photosensitizers and development of an effective second generation is continuing. Dendrimers possess architecture suitable for incorporating specific functional moieties and are a promising venue for further investigations. This review describes the use of dendrimers in PDT and how they can aid in overcoming obstacles encountered during PDT.

Keywords: Dendrimer, photodynamic therapy, PDT, photosensitizer, carrier, cancer, tumor

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