Abstract
Tea materials are widely consumed beverages in the world and are a rich source of dietary polyphenols. Catechins found in tea show excellent antioxidant potential, which is beneficial for many diseases such as cancers and cardiovascular diseases. These Tea catechins can interact with plasma proteins to form soluble or insoluble complexes, which are responsible for their bioactivities in vivo. However, there is little review published recently which focused on tea catechins-plasma protein interaction (TcPI), despite numerous articles have appeared in this field. This review summarizes the recent trend in TcPI studies focusing on metabolism, structure-affinity relationship, influence on antioxidant activity, and molecular docking aspects.
Keywords: Tea catechins, plasma proteins, structure-affinity relationship, antioxidant, molecular docking.
Current Drug Metabolism
Title:Advances on the Interaction between Tea Catechins and Plasma Proteins: Structure- Affinity Relationship, Influence on Antioxidant Activity, and Molecular Docking Aspects
Volume: 14 Issue: 4
Author(s): Hui Cao, Yujun Shi and Xiaoqing Chen
Affiliation:
Keywords: Tea catechins, plasma proteins, structure-affinity relationship, antioxidant, molecular docking.
Abstract: Tea materials are widely consumed beverages in the world and are a rich source of dietary polyphenols. Catechins found in tea show excellent antioxidant potential, which is beneficial for many diseases such as cancers and cardiovascular diseases. These Tea catechins can interact with plasma proteins to form soluble or insoluble complexes, which are responsible for their bioactivities in vivo. However, there is little review published recently which focused on tea catechins-plasma protein interaction (TcPI), despite numerous articles have appeared in this field. This review summarizes the recent trend in TcPI studies focusing on metabolism, structure-affinity relationship, influence on antioxidant activity, and molecular docking aspects.
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Cite this article as:
Cao Hui, Shi Yujun and Chen Xiaoqing, Advances on the Interaction between Tea Catechins and Plasma Proteins: Structure- Affinity Relationship, Influence on Antioxidant Activity, and Molecular Docking Aspects, Current Drug Metabolism 2013; 14 (4) . https://dx.doi.org/10.2174/1389200211314040007
DOI https://dx.doi.org/10.2174/1389200211314040007 |
Print ISSN 1389-2002 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5453 |
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Interaction between drugs and endocrine diseases
The introduction of highly active antiretroviral therapy accelerated studies and our understanding on the interaction between pharmacological therapies and endocrine diseases. Drugs can precipitate endocrine via different mechanisms, including direct alteration of hormone production and secretion, dysregulation of hormonal axis, effects on hormonal transport, receptor-binding, and cellular signalling. Common drug-induced ...read more
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