Abstract
Helicobacter pylori infection has been indicated as the main pathogenic factor in the development of chronic gastritis, peptic ulcer disease, and gastric malignancies. Although the vast majority of infected subjects do not carry but a mild, asymptomatic gastritis, still there are some cases in which the eradication of the infection appears mandatory. This review addresses current anti-Helicobacter regimens and pharmacological resources, and highlights the pros and cons of each of them, according to the most recent and reliable clinical trials. Also, basic recommendations are given, regarding treatment choice in the event of the failure of a first or second line eradicating strategy, and about the implementation of standard regimens with newer antibacterial devices as probiotics.
Keywords: H. pylori Infection, pathogenic factor, anti-Helicobacter regimens, asymptomatic gastritis
Current Medicinal Chemistry
Title: Treatment of H. pylori Infection: A Review
Volume: 12 Issue: 4
Author(s): Marcello Candelli, Enrico C. Nista, Emilia Carloni, Giulia Pignataro, Maria Assonta Zocco, Alossia Cazzato, Cristiana Di Campli, Lucia Fini, Giovanni Gasbarrini and Antonio Gasbarrini
Affiliation:
Keywords: H. pylori Infection, pathogenic factor, anti-Helicobacter regimens, asymptomatic gastritis
Abstract: Helicobacter pylori infection has been indicated as the main pathogenic factor in the development of chronic gastritis, peptic ulcer disease, and gastric malignancies. Although the vast majority of infected subjects do not carry but a mild, asymptomatic gastritis, still there are some cases in which the eradication of the infection appears mandatory. This review addresses current anti-Helicobacter regimens and pharmacological resources, and highlights the pros and cons of each of them, according to the most recent and reliable clinical trials. Also, basic recommendations are given, regarding treatment choice in the event of the failure of a first or second line eradicating strategy, and about the implementation of standard regimens with newer antibacterial devices as probiotics.
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Candelli Marcello, Nista C. Enrico, Carloni Emilia, Pignataro Giulia, Zocco Assonta Maria, Cazzato Alossia, Campli Di Cristiana, Fini Lucia, Gasbarrini Giovanni and Gasbarrini Antonio, Treatment of H. pylori Infection: A Review, Current Medicinal Chemistry 2005; 12 (4) . https://dx.doi.org/10.2174/0929867053363027
DOI https://dx.doi.org/10.2174/0929867053363027 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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