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Current Drug Metabolism


ISSN (Print): 1389-2002
ISSN (Online): 1875-5453

Separation of Ginseng Active Ingredients and their Roles in Cancer Metastasis Supplementary Therapy

Author(s): Jingjing Xie, Jingwei Shao, Yusheng Lu, Jianzhong Chen, Jichuang Wang, Suhong Yu and Lee Jia

Volume 14, Issue 5, 2013

Page: [616 - 623] Pages: 8

DOI: 10.2174/13892002113149990003

Price: $65


In Traditional Chinese Medicine (TCM), ginseng roots are taken orally as a pharmacological adaptogen and nourishing stimulants for thousands of years. Along with the rapid advancement of modern life technologies, ginseng’s effects as a non-toxic non-organspecific cancer preventive agent have recently been elucidated both at molecular levels and on clinical aspects. Here we presented some techniques used for separating ginseng active ingredients, evidence of effects of ginseng and its ingredients on cancer and cancer metastasis obtained from in vitro and in vivo experiments and thousands of volunteers participated in various clinical trials. As a biological response modifier and an adaptogen to synergistically enhance efficacy of conventional therapy as a supplement, adequate ginseng consumption reduces the risk of development of all types of cancer and the recurrence of some types of cancer, improves host intrinsic response to cancer and quality of patients’ life. We also briefly stated recent case reports on potential interaction between warfarin and ginseng products.

Keywords: Ginseng, ginsenosides, nutraceuticals, cancer prevention, metastasis.

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