Abstract
Recently, mass spectrometric related techniques have been widely applied for the identification and quantification of neurochemicals and their metabolites in biofluids. This article presents an overview of mass spectrometric techniques applied in the detection of neurological substances and their metabolites from biological samples. In addition, the advances of chromatographic methods (LC, GC and CE) coupled with mass spectrometric techniques for analysis of neurochemicals in pharmaceutical and biological samples are also discussed.
Keywords: Neurochemicals, LC-MS, GC-MS, CE-MS, MALDI-MS.
Current Neuropharmacology
Title:Recent Advances in Mass Spectrometry for the Identification of Neurochemicals and their Metabolites in Biofluids
Volume: 11 Issue: 4
Author(s): Suresh Kumar Kailasa and Hui-Fen Wu
Affiliation:
Keywords: Neurochemicals, LC-MS, GC-MS, CE-MS, MALDI-MS.
Abstract: Recently, mass spectrometric related techniques have been widely applied for the identification and quantification of neurochemicals and their metabolites in biofluids. This article presents an overview of mass spectrometric techniques applied in the detection of neurological substances and their metabolites from biological samples. In addition, the advances of chromatographic methods (LC, GC and CE) coupled with mass spectrometric techniques for analysis of neurochemicals in pharmaceutical and biological samples are also discussed.
Export Options
About this article
Cite this article as:
Kailasa Kumar Suresh and Wu Hui-Fen, Recent Advances in Mass Spectrometry for the Identification of Neurochemicals and their Metabolites in Biofluids, Current Neuropharmacology 2013; 11 (4) . https://dx.doi.org/10.2174/1570159X11311040007
DOI https://dx.doi.org/10.2174/1570159X11311040007 |
Print ISSN 1570-159X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6190 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Radiolabeled Glucocorticoids as Molecular Probes for Imaging Brain Glucocorticoid Receptors by Means of Positron Emission Tomography (PET)
Mini-Reviews in Medicinal Chemistry Mobilization and Redistribution of Default Mode Network from Resting State to Task State in Amnestic Mild Cognitive Impairment
Current Alzheimer Research New Insights in Cannabinoid Receptor Structure and Signaling
Current Molecular Pharmacology Inhibition of NF-kB Activation and Cytokines Production in THP-1 Monocytes by 2-Styrylchromones
Medicinal Chemistry The Long Non-Coding RNAs in Neurodegenerative Diseases: Novel Mechanisms of Pathogenesis
Current Alzheimer Research Age-related Changes in Pharmacodynamics: Focus on Drugs Acting on Central Nervous and Cardiovascular Systems
Current Drug Metabolism Phenanthridine Sulfonamide Derivatives as Potential DPP-IV Inhibitors: Design, Synthesis and Biological Evaluation
Current Computer-Aided Drug Design Recent Developments of the PET Imaging Agents for Metabotropic Glutamate Receptor Subtype 5
Current Topics in Medicinal Chemistry Serotonin and Cognitive Flexibility: Neuroimaging Studies into the Effect of Acute Tryptophan Depletion in Healthy Volunteers
Current Medicinal Chemistry Using Endogenous Neural Stem Cells to Enhance Recovery from Ischemic Brain Injury
Current Neurovascular Research Enhanced Selectivity Screening of GPCR Ligands Using a Label-Free Cell Based Assay Technology
Combinatorial Chemistry & High Throughput Screening NO Chimeras as Therapeutic Agents in Alzheimers Disease
Current Alzheimer Research Good at Heart: Preserving Cardiac Metabolism during aging
Current Diabetes Reviews Meet Our Regional Editor
Central Nervous System Agents in Medicinal Chemistry Neuropeptides as Possible Targets in Sleep Disorders: Special Emphasis on Hypocretin-Deficient Narcolepsy
CNS & Neurological Disorders - Drug Targets Molecular Effects of the CTG Repeats in Mutant Dystrophia Myotonica Protein Kinase Gene
Current Genomics Systemic and CNS Inflammation Crosstalk: Implications for Alzheimer’s Disease
Current Alzheimer Research Strategies Targeting Soluble β-Amyloid Oligomers and their Application to Early Diagnosis of Alzheimer’s Disease
Current Alzheimer Research The Effect of SEX/Gender on Cardiovascular Pharmacology
Current Pharmaceutical Design 7-Keto-Δ5-Steroids: Key-Molecules Owning Particular Biological and Chemical Interest
Mini-Reviews in Medicinal Chemistry