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Current Neuropharmacology


ISSN (Print): 1570-159X
ISSN (Online): 1875-6190

Recent Advances in Mass Spectrometry for the Identification of Neurochemicals and their Metabolites in Biofluids

Author(s): Suresh Kumar Kailasa and Hui-Fen Wu

Volume 11, Issue 4, 2013

Page: [436 - 464] Pages: 29

DOI: 10.2174/1570159X11311040007

Price: $65


Recently, mass spectrometric related techniques have been widely applied for the identification and quantification of neurochemicals and their metabolites in biofluids. This article presents an overview of mass spectrometric techniques applied in the detection of neurological substances and their metabolites from biological samples. In addition, the advances of chromatographic methods (LC, GC and CE) coupled with mass spectrometric techniques for analysis of neurochemicals in pharmaceutical and biological samples are also discussed.

Keywords: Neurochemicals, LC-MS, GC-MS, CE-MS, MALDI-MS.

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