Abstract
The immune system, which is indispensible for controlling neoplasias, relies on its innate and acquired immunity components to mount an effective response against tumors. In this context, dendritic cells (DCs) are seen as the best antigen-presenting cells because of their capacity for cross-presentation, which can activate both T-helper and cytotoxic lymphocytes. Thus immunotherapy with DCs is considered promising, especially for early-stage cancers. This article provides a clarifying review of recent perspectives on the development of cancer immunotherapy, which has a wide potential for therapeutic applications, and of patents related to immunotherapy with DCs.
Keywords: Cancer, dendritic cells, immunotherapy, immune response, therapeutic potential, tumor.
Recent Patents on Endocrine, Metabolic & Immune Drug Discovery
Title:Immunotherapy with Dendritic Cells as a Cancer Treatment: Perspectives and Therapeutic Potential
Volume: 7 Issue: 3
Author(s): Andre A.R. Aleixo, Márcia A. Michelin and Eddie F.C. Murta
Affiliation:
Keywords: Cancer, dendritic cells, immunotherapy, immune response, therapeutic potential, tumor.
Abstract: The immune system, which is indispensible for controlling neoplasias, relies on its innate and acquired immunity components to mount an effective response against tumors. In this context, dendritic cells (DCs) are seen as the best antigen-presenting cells because of their capacity for cross-presentation, which can activate both T-helper and cytotoxic lymphocytes. Thus immunotherapy with DCs is considered promising, especially for early-stage cancers. This article provides a clarifying review of recent perspectives on the development of cancer immunotherapy, which has a wide potential for therapeutic applications, and of patents related to immunotherapy with DCs.
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Cite this article as:
Aleixo A.R. Andre, Michelin A. Márcia and Murta F.C. Eddie, Immunotherapy with Dendritic Cells as a Cancer Treatment: Perspectives and Therapeutic Potential, Recent Patents on Endocrine, Metabolic & Immune Drug Discovery 2013; 7 (3) . https://dx.doi.org/10.2174/18722148113079990001
DOI https://dx.doi.org/10.2174/18722148113079990001 |
Print ISSN 1872-2148 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3334 |
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