Abstract
An unexpected three components reaction was developed for acridine synthesis in solvent free medium. The reaction is carried out with commercial reagents using of microwaves in a heterogeneous medium in presence of zinc chloride and 2,2-dimethoxypropane (DMP) as water scavenger. Principal advantages of the method are: short time, high yields and easy work-up.
Keywords: Aromatic acids, acridine, bernthsen reaction, diphenylamine, DMP, water scavenger.
Current Organic Synthesis
Title:A Facile and Quick Synthesis of 9-aryl-substituted-acridines Mediated by DMP
Volume: 10 Issue: 6
Author(s): George Bratulescu
Affiliation:
Keywords: Aromatic acids, acridine, bernthsen reaction, diphenylamine, DMP, water scavenger.
Abstract: An unexpected three components reaction was developed for acridine synthesis in solvent free medium. The reaction is carried out with commercial reagents using of microwaves in a heterogeneous medium in presence of zinc chloride and 2,2-dimethoxypropane (DMP) as water scavenger. Principal advantages of the method are: short time, high yields and easy work-up.
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Cite this article as:
Bratulescu George, A Facile and Quick Synthesis of 9-aryl-substituted-acridines Mediated by DMP, Current Organic Synthesis 2013; 10 (6) . https://dx.doi.org/10.2174/157017941006140206104352
DOI https://dx.doi.org/10.2174/157017941006140206104352 |
Print ISSN 1570-1794 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6271 |
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