Advances in Chromatographic Analyses of Fluoroquinolones in Pharmaceuticals and Biological Samples - A Review Article

Title: Advances in Chromatographic Analyses of Fluoroquinolones in Pharmaceuticals and Biological Samples - A Review Article

Volume: 1 Issue: 3

Author(s): Victoria F. Samanidou, Eleni A. Christodoulou and Ioannis N. Papadoyannis

Affiliation:

Keywords: fluoroquinolones, metabolites, chromatographic analyses, sample preparation, drugs, pharmaceuticals, biological samples

Abstract: Fluoroquinolones constitute a member of quinolone antibiotics, an expanding group of synthetic antibiotics, which are effective towards pathogens resistant to other antibacterials. They are broadly used for the treatment of several infections, both in human and veterinary medicine, due to their favourable kinetics and broad antibacterial activity. Herein recent advances in chromatographic methods for determination of fluoroquinolones and their metabolites are reviewed, focusing on sample pretreatment, chromatographic conditions, detection techniques, method validation and application to real samples. Results of published methods are comparatively presented and criticized.

Cite this article as:

Samanidou F. Victoria, Christodoulou A. Eleni and Papadoyannis N. Ioannis, Advances in Chromatographic Analyses of Fluoroquinolones in Pharmaceuticals and Biological Samples - A Review Article, Current Pharmaceutical Analysis 2005; 1 (3) . https://dx.doi.org/10.2174/157341205774597922