Abstract
The Victorian Centre for Functional Genomics (VCFG) is an RNAi screening facility housed at the Peter MacCallum Cancer Centre in Melbourne, Australia. The Peter Mac is Australia’s largest dedicated Cancer Research Institute, home to a team of over 520 scientists that focus on understanding the genetic risk of cancer, the molecular events regulating cancer growth and dissemination and improving detection through new diagnostic tools (www.petermac.org). Peter Mac is a well recognised technology leader and established the VCFG with a view to enabling researchers Australia and New Zealand-wide access to cutting edge functional genomics technology, infrastructure and expertise. This review documents the technology platforms operated within the VCFG and provides insight into the workflows and analysis pipelines currently in operation.
Keywords: RNAi, functional genomics, high throughput screening, high content imaging.
Combinatorial Chemistry & High Throughput Screening
Title:Functional Genomics Down Under: RNAi Screening in the Victorian Centre for Functional Genomics
Volume: 17 Issue: 4
Author(s): Daniel W. Thomas, Cathryn M. Gould, Yanny Handoko and Kaylene J. Simpson
Affiliation:
Keywords: RNAi, functional genomics, high throughput screening, high content imaging.
Abstract: The Victorian Centre for Functional Genomics (VCFG) is an RNAi screening facility housed at the Peter MacCallum Cancer Centre in Melbourne, Australia. The Peter Mac is Australia’s largest dedicated Cancer Research Institute, home to a team of over 520 scientists that focus on understanding the genetic risk of cancer, the molecular events regulating cancer growth and dissemination and improving detection through new diagnostic tools (www.petermac.org). Peter Mac is a well recognised technology leader and established the VCFG with a view to enabling researchers Australia and New Zealand-wide access to cutting edge functional genomics technology, infrastructure and expertise. This review documents the technology platforms operated within the VCFG and provides insight into the workflows and analysis pipelines currently in operation.
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Cite this article as:
Thomas W. Daniel, Gould M. Cathryn, Handoko Yanny and Simpson J. Kaylene, Functional Genomics Down Under: RNAi Screening in the Victorian Centre for Functional Genomics, Combinatorial Chemistry & High Throughput Screening 2014; 17 (4) . https://dx.doi.org/10.2174/1386207317666140323134315
DOI https://dx.doi.org/10.2174/1386207317666140323134315 |
Print ISSN 1386-2073 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5402 |
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