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Endocrine, Metabolic & Immune Disorders - Drug Targets

Editor-in-Chief

ISSN (Print): 1871-5303
ISSN (Online): 2212-3873

IL-1 as a target in inflammation

Author(s): Yuki Ito, Naoe Kaneko, Tomoyuki Iwasaki, Shinnosuke Morikawa, Kentaro Kaneko and Junya Masumoto

Volume 15, Issue 3, 2015

Page: [206 - 211] Pages: 6

DOI: 10.2174/1871530315666150316123657

Price: $65

Abstract

Inflammation is a protective response to eliminate cytotoxic agents and pathogens. Various factors are thought to be involved in the pathological changes in tissues caused by inflammation. Interleukin 1, an inflammatory cytokine, is thought to have diverse physiological functions and to play an important role in inflammatory disease. In this review, we discuss interleukin-1 as a target of inflammatory disease.

Keywords: Infectious diseases, inflammasome, inflammation, interleukin-1β, receptors, tissue.


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