Inflammation Fuels Tumor Progress and Metastasis

Title:Inflammation Fuels Tumor Progress and Metastasis

Volume: 21 Issue: 21

Author(s): Jingyi Liu, Pengnian Charles Lin and Binhua P. Zhou

Affiliation:

Keywords: Epithelial-mesenchymal transition, inflammation, metastasis.

Abstract: Inflammation is a beneficial response that can remove pathogens, repair injured tissue and restore homeostasis to damaged tissues and organs. However, increasing evidence indicate that chronic inflammation plays a pivotal role in tumor development, as well as progression, metastasis, and resistance to chemotherapy. We will review the current knowledge regarding the contribution of inflammation to epithelial mesenchymal transition. We will also provide some perspectives on the relationship between ER-stress signals and metabolism, and the role of these processes in the development of inflammation.

Cite this article as:

Liu Jingyi, Lin Charles Pengnian and Zhou P. Binhua, Inflammation Fuels Tumor Progress and Metastasis, Current Pharmaceutical Design 2015; 21 (21) . https://dx.doi.org/10.2174/1381612821666150514105741