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Anti-Cancer Agents in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1871-5206
ISSN (Online): 1875-5992

Recent Advances in Anticancer Chemotherapeutics based upon Azepine Scaffold

Author(s): Sarbjit Singh, Jail Goo, Veeraswamy Gajulapati, Tong-Shin Chang, Kyeong Lee and Yongseok Choi

Volume 16, Issue 5, 2016

Page: [539 - 557] Pages: 19

DOI: 10.2174/1871520615666150916091750

Price: $65

Abstract

In the recent few years, the emergence of heterocyclic ring-containing anti-cancer agents has gained a great deal of attention among medicinal chemists. Among these, azepine-based compounds are particularly becoming attractive recently. In this Focus Review, we highlight the recent advancements in the development of azepine-based anti-cancer compounds since the year 2000.

Keywords: Anticancer agents, azepane scaffold, chemotherapeutics, histone deacetylases, kinase inhibitors, tubulin inhibitors, phototherapeutic agents, hormone modulators.

Graphical Abstract

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