Abstract
Background: Due to the continuing increase of the elderly population in the western countries, the prevalence of the main chronic diseases (obesity, type 2 diabetes and related metabolic disorders, arterial hypertension, vascular damage due to atherosclerotic process, cancer, chronic obstructive pulmonary disease, neurodegenerative diseases, chronic kidney disease, immune-mediated diseases) is increasing. There is incontrovertible evidence that regular physical activity contributes to the primary and secondary prevention of several chronic diseases and is associated with a reduced risk of premature death.
Methods: In this review the most prevalent chronic pathologic conditions are discussed, how regular exercise may provide benefits for prevention and/or treatment of these diseases and are graphically described by means of various figures the main biological mechanisms through which exercise exerts its beneficial effects known to date.
Results: Specific interventions aimed to implement physical activity levels of the general population are of certain efficacy both for primary and secondary prevention of the major chronic diseases and constitutes an excellent cost/effective tool to improve the health status of different categories of patients.
Conclusion: Exercise represents a unique case in which a single intervention is useful against a broad range of diseases and risk factors, this knowledge should lead to an ever-increasing use of this lifestyle change.
Keywords: Regular exercise, chronic diseases, primary prevention, secondary prevention.
Current Pharmaceutical Design
Title:Preventive and Therapeutic Role of Muscle Contraction Against Chronic Diseases
Volume: 22 Issue: 30
Author(s): Domenico Di Raimondo, Gaia Musiari, Giuseppe Miceli, Valentina Arnao and Antonio Pinto
Affiliation:
Keywords: Regular exercise, chronic diseases, primary prevention, secondary prevention.
Abstract: Background: Due to the continuing increase of the elderly population in the western countries, the prevalence of the main chronic diseases (obesity, type 2 diabetes and related metabolic disorders, arterial hypertension, vascular damage due to atherosclerotic process, cancer, chronic obstructive pulmonary disease, neurodegenerative diseases, chronic kidney disease, immune-mediated diseases) is increasing. There is incontrovertible evidence that regular physical activity contributes to the primary and secondary prevention of several chronic diseases and is associated with a reduced risk of premature death.
Methods: In this review the most prevalent chronic pathologic conditions are discussed, how regular exercise may provide benefits for prevention and/or treatment of these diseases and are graphically described by means of various figures the main biological mechanisms through which exercise exerts its beneficial effects known to date.
Results: Specific interventions aimed to implement physical activity levels of the general population are of certain efficacy both for primary and secondary prevention of the major chronic diseases and constitutes an excellent cost/effective tool to improve the health status of different categories of patients.
Conclusion: Exercise represents a unique case in which a single intervention is useful against a broad range of diseases and risk factors, this knowledge should lead to an ever-increasing use of this lifestyle change.
Export Options
About this article
Cite this article as:
Raimondo Di Domenico, Musiari Gaia, Miceli Giuseppe, Arnao Valentina and Pinto Antonio, Preventive and Therapeutic Role of Muscle Contraction Against Chronic Diseases, Current Pharmaceutical Design 2016; 22 (30) . https://dx.doi.org/10.2174/1381612822666160510125011
DOI https://dx.doi.org/10.2174/1381612822666160510125011 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
Call for Papers in Thematic Issues
"Tuberculosis Prevention, Diagnosis and Drug Discovery"
The Nobel Prize-winning discoveries of Mycobacterium tuberculosis and streptomycin have enabled an appropriate diagnosis and an effective treatment of tuberculosis (TB). Since then, many newer diagnosis methods and drugs have been saving millions of lives. Despite advances in the past, TB is still a leading cause of infectious disease mortality ...read more
Current Pharmaceutical challenges in the treatment and diagnosis of neurological dysfunctions
Neurological dysfunctions (MND, ALS, MS, PD, AD, HD, ALS, Autism, OCD etc..) present significant challenges in both diagnosis and treatment, often necessitating innovative approaches and therapeutic interventions. This thematic issue aims to explore the current pharmaceutical landscape surrounding neurological disorders, shedding light on the challenges faced by researchers, clinicians, and ...read more
Emerging and re-emerging diseases
Faced with a possible endemic situation of COVID-19, the world has experienced two important phenomena, the emergence of new infectious diseases and/or the resurgence of previously eradicated infectious diseases. Furthermore, the geographic distribution of such diseases has also undergone changes. This context, in turn, may have a strong relationship with ...read more
Melanoma and Non-Melanoma Skin Cancer Treatment: Standard of Care and Recent Advances
In this thematic issue, we aim to provide a standard of care of the diagnosis and treatment of melanoma and non-melanoma skin cancer. The editor will invite authors from different countries who will write review articles of melanoma and non-melanoma skin cancers. The Diagnosis, Staging, Surgical Treatment, Non-Surgical Treatment all ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Adenosine A<sub>3</sub> Receptor: A promising therapeutic target in cardiovascular disease
Current Cardiology Reviews Preconditioning and Shear Stress in the Microcirculation in Ischemia-Reperfusion Injury
Current Cardiology Reviews Inflammatory Biomarkers in Chronic Kidney Disease: A Review
Recent Patents on Biomarkers Executive Function and Diabetes Mellitus - A Stone Left Unturned?
Current Diabetes Reviews NPY and Cardiac Diseases
Current Topics in Medicinal Chemistry Optimal Management of Hypertension in patients with Ischemic Heart Disease
Cardiovascular & Hematological Agents in Medicinal Chemistry Matrix Metalloproteinases and Colon Anastomosis Repair: A New Indication for Pharmacological Inhibition?
Mini-Reviews in Medicinal Chemistry Remodeling of the Myocardium and Potential Targets in the Collagen Degradation and Synthesis Pathways
Current Drug Targets - Cardiovascular & Hematological Disorders The Effect of Resveratrol dose and Duration of Treatment on Blood Pressure in Patients with Cardiovascular Disorders: A Systematic Review
Current Drug Discovery Technologies Age Matching Animal Models to Humans - Theoretical Considerations
Current Drug Discovery Technologies Appropriate Application of Evidence to the Care of Elderly Patients with Diabetes
Current Diabetes Reviews Combination of Therapeutic Hypothermia and Other Neuroprotective Strategies after An Ischemic Cerebral Insult
Current Neuropharmacology The Role of Coronary Physiology in Contemporary Percutaneous Coronary Interventions
Current Cardiology Reviews Lipoprotein(a): Current Perspectives
Current Vascular Pharmacology Taste and Hypertension in Humans: Targeting Cardiovascular Disease
Current Pharmaceutical Design Coronary Artery Disease and End-Stage Renal Disease - A Clinical Perspective
Current Hypertension Reviews Adenosine Receptor Ligands in Clinical Trials
Current Topics in Medicinal Chemistry Adrenomedullin in Hypertension
Current Hypertension Reviews Preface [Hot Topic:Inflammatory Markers and Mediators: Emerging Therapeutic Targets in Diabetes, Cardiovascular and Metabolic Disorders (Guest Editor: Samuel Dagogo-Jack, MD)].
Current Drug Targets Inflamm-ageing and senescence in gout: the tale of an old king’s disease.
Current Aging Science