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Mini-Reviews in Medicinal Chemistry


ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Review Article

Research Progress of Natural Product Gentiopicroside - a Secoiridoid Compound

Author(s): Shaoping Wu, Yaoyao Ning, Yingyong Zhao, Wenji Sun, Serge Thorimbert, Luc Dechoux, Matthieu Sollogoub and Yongmin Zhang

Volume 17, Issue 1, 2017

Page: [62 - 77] Pages: 16

DOI: 10.2174/1389557516666160624124127

Price: $65


Gentiopicroside is a secoiridoid compound isolated from Gentiana lutea which is called Qin Jiao in Chinese. It is one of the most common herbal medicines used in China. In this article, we review the pharmacological and biological activity (antiviral, anti-inflammatory, analgesia, antihepatotoxic and choleretic), as well as biotransformation of the gentiopicroside. In addition, attempt towards the total synthesis of gentiopicroside is also presented.

Keywords: Biological activity, biotransformation, gentiopicroside, natural product, secoiridoid, total synthesis.

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