Abstract
Background: Microwave technology is of great splendor in organic synthesis where it is applied efficaciously to synthesize a wide range of biologically active as well as industrially important compounds. Carbazole analogues are one of such important pharmacophores that are gaining considerable prominence nowadays. Besides their wide range of biological features, they possess opto-electronic as well as polymeric properties. This review highlights the entire progress of microwave assisted synthetic methodologies for carbazoles.
Methods: The key reactions are Fischer indolization, Suzuki-Miyaura cross-coupling, catalytic oxidative cyclization, cycloaddition and polymerization.
Conclusion: We have summarized a comprehensive reportage of these approaches to mild and efficient syntheses of carbazole under microwave irradiations.
Keywords: Carbazole, Microwave, Suzuki-Miyaura cross-couplings, Cadogan cyclization, Buchwald-Hartwig amination, Fischer indolization, Polymerization
Mini-Reviews in Organic Chemistry
Title:Carbazole Derivatives by Microwave Promoted Protocols: A Mini Review
Volume: 14 Issue: 6
Author(s): Zubi Sadiq*, Erum Akbar Hussain and Sadia Naz
Affiliation:
- Department of Chemistry, Lahore College for Women University, Lahore 54000,Pakistan
Keywords: Carbazole, Microwave, Suzuki-Miyaura cross-couplings, Cadogan cyclization, Buchwald-Hartwig amination, Fischer indolization, Polymerization
Abstract: Background: Microwave technology is of great splendor in organic synthesis where it is applied efficaciously to synthesize a wide range of biologically active as well as industrially important compounds. Carbazole analogues are one of such important pharmacophores that are gaining considerable prominence nowadays. Besides their wide range of biological features, they possess opto-electronic as well as polymeric properties. This review highlights the entire progress of microwave assisted synthetic methodologies for carbazoles.
Methods: The key reactions are Fischer indolization, Suzuki-Miyaura cross-coupling, catalytic oxidative cyclization, cycloaddition and polymerization.
Conclusion: We have summarized a comprehensive reportage of these approaches to mild and efficient syntheses of carbazole under microwave irradiations.
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Cite this article as:
Sadiq Zubi*, Hussain Akbar Erum and Naz Sadia , Carbazole Derivatives by Microwave Promoted Protocols: A Mini Review, Mini-Reviews in Organic Chemistry 2017; 14 (6) . https://dx.doi.org/10.2174/1570193X14666170518125756
DOI https://dx.doi.org/10.2174/1570193X14666170518125756 |
Print ISSN 1570-193X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6298 |
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