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Mini-Reviews in Medicinal Chemistry


ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Review Article

New Analogues of Aporphine Alkaloids

Author(s): Yi-Chao Ge and Kui-Wu Wang*

Volume 18, Issue 19, 2018

Page: [1590 - 1602] Pages: 13

DOI: 10.2174/1389557518666180423151426

Price: $65


Aporphine alkaloids, characterized by a heterocyclic aromatic basic skeleton, are known from different organisms and exhibit various biological activities: anti-tumor, anti-viral, anti-microbial, anti-inflammatory etc. The review gives information which provides an overview of the latest progress in the structural diversity and the biological activity of the aporphine alkaloids with their derivatives isolated from natural resource in recent years. Additionally, the synthetic approaches of aporphine alkaloids have also been reviewed.

Keywords: Aporphine alkaloid, structure, biological activity, synthetic route, anti-tumor, anti-viral, anti-microbial.

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