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Current Pharmaceutical Design

Editor-in-Chief

ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

NK Cells and Asthma

Author(s): Magnus Korsgren

Volume 8, Issue 20, 2002

Page: [1871 - 1876] Pages: 6

DOI: 10.2174/1381612023393738

Price: $65

Abstract

NK cells have been associated with immune surveillance of tumor cells and defense mechanisms against various pathogens. However, by their capacity for immunoregulation NK cells may also play a role in determining the response to allergens. The novel possibility that NK cell activity may in part decide development of allergic airway inflammation and thus potentially be involved in the inception of asthma is discussed in this review article.

Keywords: nk cells, immune surveillance of tumor cells, natural cytotoxicity, immune regulation, lymphoid cells, increased nk cell activity in asthma


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