Frontiers in Clinical Drug Research-Dementia

Volume: 2

Emerging Nanotherapeutic Strategies in Alzheimer's Disease

Author(s): Soheila Montazersaheb, Elham Ahmadian, Solmaz Maleki Dizaj, Yalda Jahanbani, Soodabeh Davaran, Irada Huseynova, Cumali Keskin, Renad I. Zhdanov, Rovshan Khalilov and Aziz Eftekhari * .

Pp: 173-203 (31)

DOI: 10.2174/9789815039474121020006

* (Excluding Mailing and Handling)


Recent nanotechnological advancements have opened new windows of hope for the treatment of neurodegenerative diseases and all of these new methods are rapidly evolving. Alzheimer's disease (AD) treatment based on neuroprotective and neurogenerative techniques has been advancing rapidly in recent decades, and the use of nanotechnology developments such as polymers, emulsions, lipo-carriers, solid lipid carriers, carbon nanotubes, and metal-based carriers has been very effective in both diagnosis and treatment methods. Targeted drug delivery is one of the most important concerns in the AD treatment approaches because the ‘blood-brain barrier’ or the ‘blood-cerebrospinal fluid barrier is a serious obstacle for delivering a therapeutic agent to the desired location, but the use of nanocarriers have provided acceptable results in this area. It seems that the use of nanotechnology in approving a successful treatment method for Alzheimer's is inevitable and this review has collected a complete copy of the recent nanotechnology-based approaches for the treatment of AD.

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