Bioactive Phytochemicals from Himalayas: A Phytotherapeutic Approach

Pharmacological, Therapeutic, and Immunomodulatory Role of Tinospora cordifolia

Author(s): Naina Rajak, Kavita, Praveen Kumar, Shikha Singh and Neha Garg * .

Pp: 89-104 (16)

DOI: 10.2174/9789815123289123010010

* (Excluding Mailing and Handling)


Tinospora cordifolia (TC, Giloy, Guduchi, or Amrita) is a valuable medicinal herb in the Indian System of Medicine (ISM), Chinese, and other traditional systems of medicine. TC contains a broad array of therapeutic phytoconstituents like alkaloids, glycosides, steroids, terpenoids, aliphatic compounds, diterpene lactones, phenolics, and flavonoids. TC is hailed for its therapeutic use with anti-inflammatory, anti-cancer, anti-diabetic, cardiac disease, anti-arthritis, and anti-microbial properties. TC induces immunomodulatory effects through the induction of macrophage activation, pro-inflammatory and anti-inflammatory cytokines, lymphocyte proliferation, and also secretion of interleukins. The present chapter highlights the biological properties, therapeutic use, and immunomodulatory pathways of Tinospora cordifolia.

Keywords: Berberine, Cancer, Giloy, Medicinal plants, Phytochemicals, Tinospora cordifolia.

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