Frontiers in Clinical Drug Research-Diabetes and Obesity

Volume: 7

Diabesity and the Kidney

Author(s): Mohamed E. Elrggal, Ahmed Elkeraie, Sol Carriazo, Hany Sawaf, Si Yuan Khor, Yasmine Elkeraie, Issa Haddad, Khaled Moustafa and Mohamed Hassanein * .

Pp: 168-207 (40)

DOI: 10.2174/9789815123586123070009

* (Excluding Mailing and Handling)

Abstract

Diabetes Mellitus and obesity, now coined as “Diabesity”, is a worldwide epidemic that imposes a huge burden on healthcare and society. Diabesity has been associated with poor outcomes and increased morbidity and mortality. The kidneys are a vulnerable target of diabesity. In this chapter, we discuss the epidemiology, pathophysiology, and treatment of diabesity–induced kidney disease. We specifically focus on the therapeutic targets and pharmacological management of diabesity-related kidney diseases. 


Keywords: Chronic kidney disease, Diabesity, Diabetes, Diabetic kidney disease, Kidney failure, Obesity.

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