Natural Immunomodulators: Promising Therapy for Disease Management

Natural Immunomodulators for Infections and Other Diseases

Author(s): Aaliya Liyakath Ali, Namrata Nailwal, Sujata Sawarkar and Gaurav Doshi * .

Pp: 243-274 (32)

DOI: 10.2174/9789815123258123010011

* (Excluding Mailing and Handling)


Infection is one of the most common occurring issues in an individual. Diseases caused by infections hamper the immune system of an individual. To modulate the immune system, immunomodulatory drugs work by either stimulating or suppressing the immune system. Several drugs like levamisole and azathioprine are available in the market today to overcome various infections. But an alternative is required to overcome the drug resistance and other side effects associated with these available drugs. To tackle these problems, many plant-based immunomodulators are being explored and have proven to be beneficial against these infections. This chapter focuses on the mechanism of action and application of natural immunomodulators like Curcumin, Resveratrol, and Genistein on various infections. The primary goal of this chapter is to understand the role of natural immunomodulators in the body for various infections and related disease conditions. With the help of findings, one can conclude that all-natural immunomodulators have areas that need attention, including their therapeutic risk-benefit ratio and their target binding affinity for various infections. However, further investigations into these drugs are necessary for a clear understanding to maximize their clinical applications 

Keywords: Natural Immunomodulators, Antimicrobial, Antibacterial, Antiviral, Antiparasitic, Ayurveda, Curcumin, Genistein, Immunosuppressants, Immunostimulants, Infection, Resveratrol.

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