The Role of Chromenes in Drug Discovery and Development

Diversity-Oriented Synthesis of Chromenes

Author(s): Atul Kumar, Diksha Rajput, Gowsia Jan and Vellaisamy Sridharan * .

Pp: 43-83 (41)

DOI: 10.2174/9789815124330123010005

* (Excluding Mailing and Handling)


Diversity-oriented synthesis (DOS) plays an important role in the construction of various natural products and the development of diverse small molecules of biological significance. In recent years, numerous diversity-oriented approaches have been demonstrated to furnish complex structures with molecular diversity from readily accessible starting materials. This chapter summarizes the recent diversity-oriented approaches based on metal-free, transition metal-catalyzed, and organocatalyzed reactions for the synthesis of chromene derivatives.

Keywords: Chromenes, Diversity-oriented synthesis, Heterocycles, Metal-free synthesis, Organocatalyzed reactions, Transition metal-catalyzed reactions.

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