Alzheimer’s disease (AD) is currently recognized as an untreatable, progressive, degenerative and terminal disease that is globally afflicting an estimated 36 million people and this number is growing in an unabated and frightening manner. Advances in Alzheimer Research, provides researchers with an integrated approach to AD academic literature ranging from basic to advanced clinical research. The series highlights the latest information in order to unravel the origin, pathogenesis and prevention of AD. The purpose of this book series is, therefore, to capture and discuss both, improvements towards the diagnosis and potential treatment of AD by established and novel strategies. This first volume of the series provides an important mechanism to bring individuals having a variety of scientific interests and expertise under one roof to specifically focus on AD and related dementias. This volume presents articles on beta amyloid protein targets as well as research on secretase enzyme systems among other topics that deal with AD therapy.

This monograph is a collection of selected articles on the subject of mood disorders such as depression and schizophrenia. It is divided into 3 sections: 1) Research methods in psychopharmacology - which highlights some established experimental techniques to study mood disorders in human and relevant animal models, 2) Pathophysiology of mood disorders – which explains the physiological and pharmacological mechanisms responsible for mood disorders and 3) New strategies for the treatment of mood disorders – a concluding section that provides recent examples on the beneficial effects of pharmacological and non-pharmacological interventions in the relief of mood disorders. The e-book serves as a primer for graduate students and researchers interested in the physiology and treatment of affective psychological disorders.

Frontiers in Clinical Drug Research - Alzheimer Disorders is an e-Book series concerned with Alzheimer's disease (AD) that causes dementia, or loss of brain function. The disease affects the parts of the brain that deal with memory, thought, and language. Chapters in each volume focus on (Alzheimer Disorders) drug research with special emphasis on clinical trials, research on drugs in advanced stages of development and cure for Alzheimer’s disease and related disorders. Frontiers in Clinical Drug Research - Alzheimer Disorders will be of particular interest to readers interested in drug therapy of this specific neurodegenerative condition and related brain disorders as the series provides relevant reviews written by experts in field of Alzheimer’s Disease research.

Frontiers in Clinical Drug Research - CNS and Neurological Disorders is an eBook series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders. The scope of the eBook series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of contemporary molecular targets involved in neurological and CNS disorders. Reviews presented in the series are mainly focused on clinical and therapeutic aspects of novel drugs intended for these targets. Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critical information for developing clinical trials and devising research plans in the field of neurology. The third volume of this series features six chapters that cover a variety of topics including: -the role of Potassium transport channels in neuroprotection against tetrahydroprotoberberines -cannabinoids in cell therapy for CNS disorders -AMPA Receptor Antagonists -therapeutic intervention in polyglutamine ataxias -nutritional therapies in neurology practice

Alzheimer’s disease (AD) is currently recognized as an untreatable, progressive, degenerative and terminal disease that is global – afflicting over 36 million people worldwide, with the number growing in an unabated and frightening manner. The goal of the series Advances in Alzheimer’s Research , with Volumes 1 and 2, is to provide an integrated approach to AD from basic and clinical research and to highlight the valuable information in order to unravel the origin, pathogenesis and prevention of AD. The aim of this book is to both capture and discuss improvements toward the diagnosis and potential treatment of AD by both established and novel strategies. This book series, including the Volume 2, provides an important mechanism to bring under the same roof a variety of scientific interests and expertise to specifically focus on AD and related dementias. The fullest attempt has been made to disseminate the most current knowledge on recent advances in potential therapy of AD.

Young Perspectives for Old Diseases is a collaborative monograph describing the current understanding of common neurodegenerative diseases. The monograph focuses on the molecular and cellular mechanisms responsible for neurodegeneration and the scientific advances that have paved the way for potential therapeutic options for patients. Reviews presented in this book present carefully validated research findings. The book begins with a section devoted to general mechanisms of neuronal death and explains the challenges of translating the scientific discoveries to the clinic. In section two, there are reviews on specific cellular dysfunctions that are common to more than one form of neurodegenerative disease, exploring the universal pathophysiology responsible for degenerating neurones. Findings on common neurodegenerative diseases are also reviewed in further detail followed by information on advances in therapeutic techniques that could be translated to a clinical setting. This book is intended as a primer as well as an update for molecular biologists and medical researchers on the mechanism of neurodegeneration and progress in the treatment of associated diseases.

Remarkable advances have been made in embolization of cerebral aneurysms, arteriovenous malformations and stroke treatment during the past decades. Endovascular techniques are less invasive than other forms of neurosurgery. However, endovascular neurosurgery is becoming more complicated as the technology is becoming more sophisticated. Frontiers in Neurosurgery is an ebook series which triggers principle issues that still fuel debate in neurosurgery. The series is intended as a reference for practicing endovascular neurosurgeons, vascular neurosurgeons, interventional neurologists and neuroradiologists who have a solid knowledge of neuroangiography. </p><p> The first volume of this series brings reviews on a variety of challenges that neuroendovascular surgeons can face such as: - Devices for Neuroendovascular Treatment - Dual Antiplatelet Therapy in Neuroendovascular Procedures - Endovascular Reperfusion Management for Acute Ischemic Stroke - Spinal Vascular Pathology - Anesthesia Options for Endovascular Neurosurgery … and much more.

How do neurons work in processes that guide thought and action? This eBook answers this question by presenting an accurate analysis of all the physico-chemical phenomena occurring between interconnected neurons. Once researchers have this information, they can then build a functional catalog of neurons and understand the working behind the simplest physiological elements and these can hopefully be replicated into devices. Microscopic and macroscopic experimental results can assist in the study of sensorial analysis, instincts and motor control of skeletal muscles. The book also presents a description of memory at the cellular level and gives insights about the learning process in living systems. Such research has increased our understanding of the mechanisms of animal behaviors from the honeybee to the dog. In human beings, the efficiency of the same neural mechanisms overtakes a threshold when language allows building new abstract signals from previous abstract signals. Introduction to the Neural Basis of Action and Thought demonstrates to readers how physiological processes allow us to recall words and generate sentences and how these processes support abstract thought, action and self awareness. This book is a useful primer for anyone interested in cognitive sciences and related research.

Frontiers in Clinical Drug Research - Alzheimer Disorders is an e-Book series concerned with Alzheimer's disease (AD) that causes dementia, or loss of brain function. The disease affects the parts of the brain that deal with memory, thought, and language. Chapters in each volume focus on (Alzheimer Disorders) drug research with special emphasis on clinical trials, research on drugs in advanced stages of development and cure for Alzheimer’s disease and related disorders. Frontiers in Clinical Drug Research - Alzheimer Disorders will be of particular interest to readers interested in drug therapy of this specific neurodegenerative condition and related brain disorders as the series provides relevant reviews written by experts in field of Alzheimers Disease research. The third volume of this series features research on -perfusional modifications in prodromal Alzheimer's disease, -BACE inhibition treatment, -frontotemporal dementia caused by progranulin mutations -evidence-based treatment for psychological symptoms of Alzheimer’s Disease

Frontiers in Clinical Drug Research - Alzheimer Disorders is an e-Book series concerned with Alzheimer's disease (AD) that causes dementia, or loss of brain function. The disease affects the parts of the brain that deal with memory, thought, and language. Chapters in each volume focus on (Alzheimer Disorders) drug research with special emphasis on clinical trials, research on drugs in advanced stages of development and cure for Alzheimer’s disease and related disorders. Frontiers in Clinical Drug Research - Alzheimer Disorders will be of particular interest to readers interested in drug therapy of this specific neurodegenerative condition and related brain disorders as the series provides relevant reviews written by experts in field of Alzheimer’s Disease research. The fourth volume of this series features research on - Melatoninergic Pathways in Alzheimer's disease, - Nutritional Approaches in Alzheimer’s disease prevention, - Updates on drugs and strategies for Alzheimer’s disease prevention