Abstract
Depression is a common psychiatric disorder and a leading cause of disability worldwide. Traditional Chinese medicine is one of the commonly used complementary and alternative medicine therapies for depression. Clinical trials have been carried out to assess the efficacy and safety of Chinese herbal medicine currently. The exploration of herbal mechanisms of action used for the treatment of depression has also received great attention. This study is performed to summarize the frequently used formulae, patent drugs and single herbs in treating depression, review the literatures of clinical trials in treating depressive disorders, and to list the possible mechanisms involved during the treatment. Besides, we will analyze the limitations of present studies and the obstacles in the modernization of traditional Chinese medicine.
Keywords: Depression, traditional Chinese medicine, clinical trials, therapeutic mechanisms, modernization, review.
Current Pharmaceutical Design
Title:Chinese Herbal Medicine for the Treatment of Depression: Applications, Efficacies and Mechanisms
Volume: 23 Issue: 34
Author(s): Yuanyuan Wang, Menglin Li, Yan Liang, Yiting Yang, Zhe Liu, Keyu Yao, Zijie Chen and Shuangqing Zhai*
Affiliation:
- School of Basic Medical Science, Beijing University of Chinese Medicine, Beijing 100029,China
Keywords: Depression, traditional Chinese medicine, clinical trials, therapeutic mechanisms, modernization, review.
Abstract: Depression is a common psychiatric disorder and a leading cause of disability worldwide. Traditional Chinese medicine is one of the commonly used complementary and alternative medicine therapies for depression. Clinical trials have been carried out to assess the efficacy and safety of Chinese herbal medicine currently. The exploration of herbal mechanisms of action used for the treatment of depression has also received great attention. This study is performed to summarize the frequently used formulae, patent drugs and single herbs in treating depression, review the literatures of clinical trials in treating depressive disorders, and to list the possible mechanisms involved during the treatment. Besides, we will analyze the limitations of present studies and the obstacles in the modernization of traditional Chinese medicine.
Export Options
About this article
Cite this article as:
Wang Yuanyuan , Li Menglin , Liang Yan , Yang Yiting , Liu Zhe , Yao Keyu , Chen Zijie and Zhai Shuangqing *, Chinese Herbal Medicine for the Treatment of Depression: Applications, Efficacies and Mechanisms, Current Pharmaceutical Design 2017; 23 (34) . https://dx.doi.org/10.2174/1381612823666170918120018
DOI https://dx.doi.org/10.2174/1381612823666170918120018 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Interactions between Personality, Depression, Anxiety and Cognition to Understand Early Stage of Alzheimer’s Disease
Current Topics in Medicinal Chemistry Drug Targets in Stress-Related Disorders
Current Medicinal Chemistry Application of Simplex Optimization in the Development of an On-line Preconcentration System for the Determination of Cu in Human Hair Samples Using FAAS
Current Analytical Chemistry In Vivo Transdermal Delivery of Leuprolide Using Microneedles and Iontophoresis
Current Pharmaceutical Biotechnology Destruction as a Means of Survival: The Paradigm of Modern Psychopathology
Adolescent Psychiatry <i>LncRNA</i> Xist, X-chromosome Instability and Alzheimer’s Disease
Current Alzheimer Research Evaluation of Selected Natural Compounds as Dual Inhibitors of Catechol-O-Methyltransferase and Monoamine Oxidase
Central Nervous System Agents in Medicinal Chemistry NF-κB Signaling and Carcinogenesis
Current Pharmaceutical Design Dichotomous Life of DNA Binding High Mobility Group Box1 Protein in Human Health and Disease
Current Protein & Peptide Science Microglial Proteases: Strategic Targets for Neuroprotective Agents
Current Neuropharmacology Wavelet Transform Based Algorithm for Automatic Detection of Patient- Specific Single Spike-and-Wave Discharges in Simulated Real-Time Conditions
Neuroscience and Biomedical Engineering (Discontinued) Leukocyte Function-Associated Antigen-1: Structure, Function and Application Prospects
Protein & Peptide Letters Clinical Application of Tissue Doppler Imaging in Coronary Artery Diseases and Heart Failure
Recent Patents on Medical Imaging Application in Electrochemistry of Graphene-Modified Electrodes
Micro and Nanosystems Bis(thiosemicarbazone) Metal Complexes as Therapeutics for Neurodegenerative Diseases
Current Topics in Medicinal Chemistry Understanding the Metabolic Consequences of Human Arylsulfatase A Deficiency through a Computational Systems Biology Study
Central Nervous System Agents in Medicinal Chemistry Longitudinal Association between White Matter Hyperintensities and White Matter Beta-Amyloid Deposition in Cognitively Unimpaired Elderly
Current Alzheimer Research Hallmarks in the Therapeutic Approach of Aortic Aneurysms: The Main Contributors
Current Pharmaceutical Design Ion Exchange Resins Transforming Drug Delivery Systems
Current Drug Delivery Editorial Thematic Issue: Targeting Synaptic Dysfunction and Neural Connectivity in Neurological and Psychiatric Disorders
Current Pharmaceutical Design