Abstract
Molecular exclusion HPLC chromatography on a Protein Pak SW 300 column and reversed phase HPLC on a µ-Bondapack Cl8 column were used to purify four novel neurotoxins (rom the crotoxin complex, and five crotoxin subunits (PLA2 and crotapotin) as well as two crotamine isoforms. A single preparative reversed phase HPLC steps yielded a major basic myotoxin followed by the subunits of crotoxin (three PLA2 isoforms and two crotapotin isoforms). This modified procedure may be useful for the rapid, large-scale purification of toxins from Crotalid venoms.
Call for Papers in Thematic Issues
Advancing the Understanding of Regulatory Mechanisms and Diseases Through Biochemistry and Structural Biology
Modern research is increasingly interested in understanding the regulatory mechanisms and diseases through various integrative approaches. Biochemistry and structural biology offer valuable atomic-level insights that help unravel the complexities of cellular regulatory mechanisms and their association with health and disease. The unique advantage of these fields is that they provide ...read more
Protein Based Biomaterials in Environmental Sustainability, Therapy, and Diagnostics
Protein-based biomaterials have wide variety of therapeutic and diagnostic applications. Important properties of these materials are biocompatibility, biodegradability, functional versatility, and ability to interact with life. They are biodegradable so make sought after targets for environmental applications. These materials are also being investigated for increased applications in water filtration technology ...read more
Recent Advances in Protein Engineering and Design
Protein engineering and design have revolutionized biotechnology, medicine, and industrial applications by enabling the creation of novel proteins with tailored functions. Recent advancements in computational modeling, directed evolution, and synthetic biology have expanded the possibilities for engineering proteins with enhanced stability, specificity, and activity. This special issue will explore state-of-the-art ...read more
Therapeutic Proteins and Peptides of Plant Origin
Plants are still the major repository of biologically active substances. In the last two decades, however, natural peptides and proteins of plant origin have gained increasing attention due to their pharmacological activities over a variety of human illnesses, including those mediated by infections and parasitosis and those involving different cellular ...read more
Related Books
Wild Vegetables: Morphology, Phytochemistry and Utility Part 1
Biology for Students
Medicinal Plants of Pilibhit Tiger Reserve (PTR) India
Plant-Microbe Interactions: A Comprehensive Review
Glycosylation and Glycation in Health and Diseases
Phytogenic and Phytochemical as Alternative Feed Additives for Animal Production
Methods and Techniques in Nematology
Mind Maps in Clinical Biochemistry
A Treatise on Ecological Science
From SARS-CoV to MARS-CoV
1
