Abstract
Due to the high affinity of metallothioneins (MTs) toward various transition metal ions, MTs play an important role in regulation of essential metals, detoxification of heavy metals, and scavenging of free radicals. In this review, we focus on the recent development on the metal release from and sequestration by MTs characterized by electrochemistry and surface plasmon resonance (SPR). The investigation of metal release and coordination processes is of great significance in illustrating the intriguing role of MTs in environmental toxicology.
Keywords: Metallothionein, metal release, sequestration, electrochemistry, surface plasmon resonance
Current Pharmaceutical Biotechnology
Title: Metal Release from and Sequestration by Metallothioneins Monitored by Electrochemistry and SPR
Volume: 12 Issue: 5
Author(s): Lin Liu and Jianxiu Wang
Affiliation:
Keywords: Metallothionein, metal release, sequestration, electrochemistry, surface plasmon resonance
Abstract: Due to the high affinity of metallothioneins (MTs) toward various transition metal ions, MTs play an important role in regulation of essential metals, detoxification of heavy metals, and scavenging of free radicals. In this review, we focus on the recent development on the metal release from and sequestration by MTs characterized by electrochemistry and surface plasmon resonance (SPR). The investigation of metal release and coordination processes is of great significance in illustrating the intriguing role of MTs in environmental toxicology.
Export Options
About this article
Cite this article as:
Liu Lin and Wang Jianxiu, Metal Release from and Sequestration by Metallothioneins Monitored by Electrochemistry and SPR, Current Pharmaceutical Biotechnology 2011; 12 (5) . https://dx.doi.org/10.2174/138920111795470886
DOI https://dx.doi.org/10.2174/138920111795470886 |
Print ISSN 1389-2010 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4316 |
Call for Papers in Thematic Issues
25th Anniversary Special Issue.
Current Pharmaceutical Biotechnology (CPB) is celebrating its 25th anniversary with a special issue highlighting the journal’s growth and its pivotal contributions to innovation and knowledge in academia. Since its inaugural issue in 2000, CPB has fostered a multidisciplinary platform for emerging scholars to publish high-quality research in pharmaceutical biotechnology. Over ...read more
Artificial Intelligence in Bioinformatics
Bioinformatics is an interdisciplinary field that analyzes and explores biological data. This field combines biology and information system. Artificial Intelligence (AI) has attracted great attention as it tries to replicate human intelligence. It has become common technology for analyzing and solving complex data and problems and encompasses sub-fields of machine ...read more
Latest Advancements in Biotherapeutics.
The scope of this thematic issue is to comprehensively explore the rapidly evolving landscape of biotherapeutics, emphasizing breakthroughs in precision medicine. Encompassing diverse therapeutic modalities, the issue will delve into the latest developments in monoclonal antibodies, CRISPR/Cas gene editing, CAR-T cell therapies, and innovative drug delivery systems, such as nanoparticle-based ...read more
Machine Learning and Artificial Intelligence for Medical Data Analysis and Human Information Analysis in Healthcare
The intersection of machine learning (ML) and artificial intelligence (AI) with the pharmaceutical industry is revolutionizing traditional paradigms in drug discovery and development. These technologies have introduced innovative approaches to analyzing complex datasets and predicting chemical properties, leading to more efficient identification and optimization of drug candidates. By employing sophisticated ...read more

- Author Guidelines
- Bentham Author Support Services (BASS)
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Relaxed Statistical Shape Models for 3D Image Segmentation – Application to Mandible Bone in Cone-beam CT Data
Current Medical Imaging Potential of Recombinant SV40-Based Vectors for Gene Therapy
Recent Patents on DNA & Gene Sequences Radioimmunotherapy of Infection with 213Bi-Labeled Antibodies
Current Radiopharmaceuticals Copper Complexes as Anticancer Agents
Anti-Cancer Agents in Medicinal Chemistry Metal Complexes as Promising Agents for Biomedical Applications
Current Medicinal Chemistry The Role of Insulin Receptor Isoforms and Hybrid Insulin/IGF-I Receptors in Human Cancer
Current Pharmaceutical Design QSRR and QSAR Studies of Antitumor Drugs in View of their Biological Activity Prediction
Medicinal Chemistry Opioid Alkaloids in Fire Poppies, Papaver Californicum
The Natural Products Journal A High Throughput Scintillation Proximity Imaging Assay for Protein Methyltransferases
Combinatorial Chemistry & High Throughput Screening Chemoinformatic Analysis of Biologically Active Macrocycles
Current Topics in Medicinal Chemistry Microbial Exo-Polysaccharides for Biomedical Applications
Mini-Reviews in Medicinal Chemistry Mathematical Nanotoxicoproteomics: Quantitative Characterization of Effects of Multi-walled Carbon Nanotubes (MWCNT) and TiO2 Nanobelts (TiO2-NB) on Protein Expression Patterns in Human Intestinal Cells
Current Computer-Aided Drug Design Aptamer-Based Carbohydrate Recognition
Current Pharmaceutical Design The Impact of Malnutrition on the Peripheral Serotoninergic System in Anorexia Nervosa: A Systematic Review
Current Psychiatry Reviews Sucrose Hydrolytic Enzymes: Old Enzymes for New Uses as Biocatalysts for Medical Applications
Current Topics in Medicinal Chemistry Circulating MicroRNAs as a New Class of Biomarkers of Physiological Reactions of the Organism to the Intake of Dietary Supplements and Drugs
MicroRNA Daphnane-Type Diterpene Orthoesters and their Biological Activities
Mini-Reviews in Medicinal Chemistry The Role of Transesophageal Echocardiography in the Intraoperative Period
Current Cardiology Reviews Polymeric Systems as Nanodevices for siRNA Delivery
Current Gene Therapy Overexpression and Characterization of the C-Terminal Domain of Human SIVA1: A Proapoptotic Factor and Cytoskeleton Binding Protein
Protein & Peptide Letters