Abstract
A series of 7-carbamate derivatives of quercetin were synthesized. Using dichlorodiphenylmethane and benzyl bromide to partly protect the hydroxyl groups, the protected quercetin then reacted with amino acid ester isocyanates, deprotection the hydroxyls with hydrogen using a palladium on carbon catalyst, then treating with ammonia gas to give the ammonium salts of 7-carbamate derivatives of quercetin.
Keywords: Quercetin, 7-carbamate derivatives of quercetin, dichlorodiphenylmethane, isocyanate, ammonium salt
Letters in Organic Chemistry
Title: Syntheses of the Ammonium Salts of 7-Carbamate Derivatives of Quercetin
Volume: 4 Issue: 5
Author(s): Chenglong Wu, Li Cheng, Ying Li, Dong Guo, Shuyan Yu, Xianxue Wu and Yuquan Wei
Affiliation:
Keywords: Quercetin, 7-carbamate derivatives of quercetin, dichlorodiphenylmethane, isocyanate, ammonium salt
Abstract: A series of 7-carbamate derivatives of quercetin were synthesized. Using dichlorodiphenylmethane and benzyl bromide to partly protect the hydroxyl groups, the protected quercetin then reacted with amino acid ester isocyanates, deprotection the hydroxyls with hydrogen using a palladium on carbon catalyst, then treating with ammonia gas to give the ammonium salts of 7-carbamate derivatives of quercetin.
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Cite this article as:
Chenglong Wu , Li Cheng , Ying Li , Dong Guo , Shuyan Yu , Xianxue Wu and Yuquan Wei , Syntheses of the Ammonium Salts of 7-Carbamate Derivatives of Quercetin, Letters in Organic Chemistry 2007; 4 (5) . https://dx.doi.org/10.2174/157017807781212021
DOI https://dx.doi.org/10.2174/157017807781212021 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
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