Pentacyclic Triterpenoids and Their Saponins with Apoptosis-Inducing Activity

Adaptogens are pharmacologically active compounds or plant extracts that are associated with the ability to enhance the body’s stability against stress. The intake of adaptogens is associated not only with a better ability to adapt to stress and maintain or normalise metabolic functions but also with better mental and physical ...read more

AlphaFold, a groundbreaking AI tool for protein structure prediction, is revolutionizing drug discovery. Its near-atomic accuracy unlocks new avenues for designing targeted drugs and performing efficient virtual screening. However, AlphaFold's static predictions lack the dynamic nature of proteins, crucial for understanding drug action. This is especially true for multi-domain proteins, ...read more

The title "Artificial Intelligence and In Silico Strategies for Novel Target Identification in Alzheimer's Disease" emphasizes the use of Artificial intelligence (AI) and advanced in silico methods to address Alzheimer's disease (AD), a neurodegenerative condition that currently has few effective treatments. AI and insilico methods, including molecular modeling, simulations, are ...read more

Our approach involves using computational methods to predict the potential therapeutic benefits of natural products by considering factors such as drug structure, targets, and interactions. We also employ multitarget analysis to understand the role of drug targets in disease pathways. We advocate for the use of artificial intelligence in predicting ...read more