Abstract
Despite the success in antimicrobial development, the rapid emergence of pathogenic bacteria resistance to conventional antibiotics calls for an increased focus on the purification and characterization of new antimicrobials. Antimicrobial peptides (AMPs) are promising candidates in future therapeutics. In addition to their broad array of antimicrobial activity, these peptides show multi advent function to human health. The marine environment is relatively poorly explored in terms of potential pharmaceuticals. It contains a tremendous organism diversity which would be a good source of novel AMPs. In this present review we discuss recent antimicrobial peptides isolated from both marine fish and marine invertebrates. We also mention the isolation and benefit of these marine-derived natural antibiotics.
Keywords: Antimicrobial peptides, marine fish, marine invertebrates, peptide structure and function.
Current Protein & Peptide Science
Title:Antimicrobial Peptides from Marine Sources
Volume: 14 Issue: 3
Author(s): Van L.T. Hoang and Se-Kwon Kim
Affiliation:
Keywords: Antimicrobial peptides, marine fish, marine invertebrates, peptide structure and function.
Abstract: Despite the success in antimicrobial development, the rapid emergence of pathogenic bacteria resistance to conventional antibiotics calls for an increased focus on the purification and characterization of new antimicrobials. Antimicrobial peptides (AMPs) are promising candidates in future therapeutics. In addition to their broad array of antimicrobial activity, these peptides show multi advent function to human health. The marine environment is relatively poorly explored in terms of potential pharmaceuticals. It contains a tremendous organism diversity which would be a good source of novel AMPs. In this present review we discuss recent antimicrobial peptides isolated from both marine fish and marine invertebrates. We also mention the isolation and benefit of these marine-derived natural antibiotics.
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Cite this article as:
Hoang L.T. Van and Kim Se-Kwon, Antimicrobial Peptides from Marine Sources, Current Protein & Peptide Science 2013; 14 (3) . https://dx.doi.org/10.2174/13892037113149990037
| DOI https://dx.doi.org/10.2174/13892037113149990037 |
Print ISSN 1389-2037 |
| Publisher Name Bentham Science Publisher |
Online ISSN 1875-5550 |
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Peptide and Peptidomimetics: Structure, Assembly, and Applications
Peptides are fundamental biomolecules, imparting structural support, biochemical regulation, and potent pharmacological activity. The therapeutic significance of peptides and peptidomimetics was first demonstrated by the discovery of Insulin, leading to the development of clinically important agents such as Captopril, Semaglutide, and Goserelin, and the antibiotic Lariocidin. Progress in peptide chemistry ...read more
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