Abstract
Functional biomaterials able to sense and respond to biotic and abiotic stimuli are currently clustered in the category of smart materials. Polymers represent the most investigated class of materials able to change different morphological, functional, architectural and biological properties as a feedback to an external inducing element. Although very useful in most industrial, biotechnological and ecological approaches, biopolymers bring important and intriguing impact in medicine. Numerous applications, ranging from tissue engineering to drug delivery have been recently emerged as a result of the technological progress made in the field of polymer engineering. Most interesting approaches refer to the development of intelligent targeting approaches and the design of tailored biopolymeric scaffolds utilized in therapy. The purpose of this review paper is to bring together and discuss the most recent knowledge regarding applications of smart biopolymers in biomedical scaffolding and drug delivery. Current progress made on the field of tissue engineering, cancer therapy and alternative antimicrobial approaches are highlighted.
Keywords: Smart polymers, drug delivery, intelligent scaffolding, cancer therapy, alternative antimicrobials.
Current Organic Chemistry
Title:Biopolymers Tailored For Intelligent Scaffolding and Drug Delivery
Volume: 20 Issue: 28
Author(s): Lia-Mara Ditu, Veronica Lazar, Alexandru M. Grumezescu and Alina M. Holban
Affiliation:
Keywords: Smart polymers, drug delivery, intelligent scaffolding, cancer therapy, alternative antimicrobials.
Abstract: Functional biomaterials able to sense and respond to biotic and abiotic stimuli are currently clustered in the category of smart materials. Polymers represent the most investigated class of materials able to change different morphological, functional, architectural and biological properties as a feedback to an external inducing element. Although very useful in most industrial, biotechnological and ecological approaches, biopolymers bring important and intriguing impact in medicine. Numerous applications, ranging from tissue engineering to drug delivery have been recently emerged as a result of the technological progress made in the field of polymer engineering. Most interesting approaches refer to the development of intelligent targeting approaches and the design of tailored biopolymeric scaffolds utilized in therapy. The purpose of this review paper is to bring together and discuss the most recent knowledge regarding applications of smart biopolymers in biomedical scaffolding and drug delivery. Current progress made on the field of tissue engineering, cancer therapy and alternative antimicrobial approaches are highlighted.
Export Options
About this article
Cite this article as:
Ditu Lia-Mara, Lazar Veronica, Grumezescu M. Alexandru and Holban M. Alina, Biopolymers Tailored For Intelligent Scaffolding and Drug Delivery, Current Organic Chemistry 2016; 20 (28) . https://dx.doi.org/10.2174/1385272820666160511103622
DOI https://dx.doi.org/10.2174/1385272820666160511103622 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
Call for Papers in Thematic Issues
From Lab Bench to Algorithm: The Future of Organic Chemistry Powered by AI
Organic chemistry, with its intricate dance of molecules and reactions, is undergoing a transformation fuelled by the power of Artificial Intelligence (AI) and Machine Learning (ML). The integration of AI/ML with Organic Chemistry is revolutionizing the field by enhancing the efficiency and accuracy of chemical research and development. These technologies ...read more
Hybrid-Materials Catalyzed Conversion of Molecules and Substances
To address the global energy and environmental issues, and inspired by the photosynthesis of plants, scientists have material shifted their focus from traditional chemistry to novel ones to discover new substances and molecules. Hybrid materials with their unique synergistic effects, interface regulation capabilities, and functional integration have emerged as a ...read more
Natural terpenes: The Chemistry and Biological Significance
Natural organic compounds such as alkaloid, flavonoid, terpene, protein, and saccharide have been widely applied in the fields of medicine, food supplements, agriculture, cosmetics and material sciences. Terpenes as an important natural products present intensively structural diversity and widely pharmacological properties. As an important origin of medicine, the chemistry and ...read more
Porphyrazine, its Analogues and Their Metalcomplexes: Theoretical Consideration and Experimental Data
Porphyrazines are specific analogues of porphyrins – macrocyclic compounds with tetrapyrrole macrocycles, which are key components of a number of natural compounds, in particular chlorophyll and heme, playing a decisive role in the processes of reversible transfer of oxygen molecules in living organisms. They differ from porphyrins in that their ...read more
Related Journals

- Author Guidelines
- Bentham Author Support Services (BASS)
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
The Risk That DSM-5 Will Promote Even More Inappropriate Antipsychotic Exposure In Children and Teenagers
Current Psychiatry Reviews 18FDG-PET/CT in Traumatic Brain Injury Patients: The Relative Hypermetabolism of Vermis Cerebelli as a Medium and Long Term Predictor of Outcome
Current Radiopharmaceuticals Heat Shock Protein 90 – a Potential Target in the Treatment of Human Acute Myelogenous Leukemia
Current Cancer Drug Targets Cannabinoids: Novel Medicines for the Treatment of Huntingtons Disease
Recent Patents on CNS Drug Discovery (Discontinued) Models of Change in Schizophrenia: One for All, or All for Some?
Current Psychiatry Reviews M1 Agonists as a Potential Disease-Modifying Therapy for Alzheimers Disease
Current Alzheimer Research Diagnostic and Therapeutic Uses of Nanomaterials in the Brain
Current Medicinal Chemistry Changes in Body Composition of Old Rats at Different Time Points After Dexamethasone Administration
Current Aging Science de Quervain’s Tenosynovitis with Accessory Abductor Pollicis Longus Tendon and <i>‘Wartenberg’s syndrome’</i> - A Case Report
Current Rheumatology Reviews Transient Blood Brain Barrier Disruption Induced by Oleic Acid is Mediated by Nitric Oxide
Current Neurovascular Research Homocysteine Level and Mechanisms of Injury in Parkinson's Disease as Related to MTHFR, MTR, and MTHFD1 Genes Polymorphisms and LDopa Treatment
Current Genomics Addictions and Stress: Clues for Cocaine Pharmacotherapies
Current Pharmaceutical Design The Intestinal Environment in Health and Disease – Recent Insights on the Potential of Intestinal Bacteria to Influence Human Health
Current Pharmaceutical Design Mechanisms of Cortical Neural Synchronization Related to Healthy and Impaired Consciousness: Evidence by Quantitative Electroencephalographic Studies
Current Pharmaceutical Design On the Use of Hydrogels in Cell Encapsulation and Tissue Engineering Systems
Recent Patents on Drug Delivery & Formulation Diabetic Retinopathy: Current and New Treatment Options
Current Diabetes Reviews Translational Multimodality Neuroimaging
Current Drug Targets The Neuropharmacology of (-)-Stepholidine and its Potential Applications
Current Neuropharmacology The Mechanism of the Beneficial Effect of Botulinum Toxin Type a Used in the Treatment of Temporomandibular Joints Dysfunction
Mini-Reviews in Medicinal Chemistry Antipsychotic Profile of Cannabidiol and Rimonabant in an Animal Model of Emotional Context Processing in Schizophrenia
Current Pharmaceutical Design