Abstract
Functional biomaterials able to sense and respond to biotic and abiotic stimuli are currently clustered in the category of smart materials. Polymers represent the most investigated class of materials able to change different morphological, functional, architectural and biological properties as a feedback to an external inducing element. Although very useful in most industrial, biotechnological and ecological approaches, biopolymers bring important and intriguing impact in medicine. Numerous applications, ranging from tissue engineering to drug delivery have been recently emerged as a result of the technological progress made in the field of polymer engineering. Most interesting approaches refer to the development of intelligent targeting approaches and the design of tailored biopolymeric scaffolds utilized in therapy. The purpose of this review paper is to bring together and discuss the most recent knowledge regarding applications of smart biopolymers in biomedical scaffolding and drug delivery. Current progress made on the field of tissue engineering, cancer therapy and alternative antimicrobial approaches are highlighted.
Keywords: Smart polymers, drug delivery, intelligent scaffolding, cancer therapy, alternative antimicrobials.
Graphical Abstract
Call for Papers in Thematic Issues
Advances and Applications of Enantioselective Organic Synthesis.
The development of enantioselective synthetic methodologies remains a cornerstone of modern organic chemistry, enabling the precise construction of chiral molecules with profound impact in pharmaceuticals, agrochemicals, and materials science. This thematic issue, Advances and Applications of Enantioselective Organic Synthesis, highlights recent progress in catalytic strategies, including organocatalysis, metal-based catalysis, and ...read more
Design and Functionalization of Nitrogen-Containing Aromatic Heterocycles: New Synthetic Reactions, Mechanistic Insights, and Spectroscopic Characterization
Nitrogen-containing aromatic heterocycles are key structural motifs in numerous biologically active molecules, and their diverse architectures support a broad spectrum of pharmacological applications. These systems have been extensively explored for their anticancer, antiviral, and antiretroviral activities, with particular promise in anti-HIV research. Beyond medicinal chemistry, their design and functionalization enable ...read more
Emerging Catalytic Strategies in Heterocyclic Chemistry
Heterocyclic chemistry remains at the heart of organic synthesis, with profound applications in pharmaceuticals, agrochemicals, and functional materials. Recent advances in catalysis, including photocatalysis, electrocatalysis, transition-metal catalysis, and nanomaterial-based approaches, are reshaping the synthesis and functionalization of heterocycles. These strategies offer enhanced selectivity, sustainability, and versatility, providing novel pathways for ...read more
Hybrid-Materials Catalyzed Conversion of Molecules and Substances
To address the global energy and environmental issues, and inspired by the photosynthesis of plants, scientists have material shifted their focus from traditional chemistry to novel ones to discover new substances and molecules. Hybrid materials with their unique synergistic effects, interface regulation capabilities, and functional integration have emerged as a ...read more
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