Research Methodology and Project Management in Biotechnology

Genomics and Proteomics

Author(s): Simmi Kharb*, Akshat Singh*, Abhyuday Singh* and Deepa Kharb * .

Pp: 266-299 (34)

DOI: 10.2174/9789815080742123010010

* (Excluding Mailing and Handling)


Genomics is the science of mapping sequences and analysing genomes. This chapter gives an overview of techniques of genome sequencing, gene mapping, sequence analysis, DNA sequencing and microarrays. Genomics offers sequencing, mapping, and analysis of a genome. With the help of computer-based techniques, a human genome was sequenced. Now it is possible to identify the function of genes from protein databases. Since proteins cannot be amplified like nucleic acid, the analysis of protein expression is challenging 2 DGE; MS and protein chips are the most widely used technologies for proteome analysis.

Keywords: Genomics, Proteomics, Metabolomics, Transcriptome, Metabolome Database, Protein expression, Heterologous proteins.

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