Abstract
An image-based QSAR approach, called Multivariate Image Analysis Applied to Quantitative Structure-Activity Relationships (MIA-QSAR) is described as a tool to model the toxicities of a series of organotin compounds against Aedes aegypti and Anopheles stephensi mosquito larvae, vectors of dengue and yellow fever. This methodology may help researchers to discover novel, potent mosquito controllers.
Keywords: QSAR-2D, MIA-QSAR, dengue and yellow fever.
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Cite this chapter as:
Matheus P. Freitas, Teodorico C. Ramalho, Elaine F. F. da Cunha, Rodrigo A. Cormanich ;Multivariate Image Analysis Applied to QSAR as a Tool for Mosquitoes Control: Dengue and Yellow Fever, Chemoinformatics: Directions Toward Combating Neglected Diseases (2012) 1: 154. https://doi.org/10.2174/978160805183011201010154
DOI https://doi.org/10.2174/978160805183011201010154 |
Publisher Name Bentham Science Publisher |