An Electromagnetic Spectrum
Page: 1-8 (8)
Author: Manisha C. Kotadiya*
DOI: 10.2174/9789815313239124010003
PDF Price: $15
Abstract
Spectroscopy has historically played an important role in the development of atomic theory, and it is currently widely utilised in basic research. In forensic laboratories, spectroscopic methods are commonly employed for quantitative and qualitative analysis. This chapter gives an overview of the fundamental concepts of spectroscopy as they apply to analytical measurements.
Ultraviolet and Visible Spectroscopy
Page: 9-33 (25)
Author: Manisha C. Kotadiya*
DOI: 10.2174/9789815313239124010004
PDF Price: $15
Abstract
Ultraviolet and Visible spectroscopy was one of the first instrumental methods for analysis. It may be used to characterise a wide range of materials. The UV-Vis provides information based on the degree of absorption or transmittance of a variable wavelength of beam light and sample responses. The general law known as Beer's law may be used to quantitatively quantify the absorption of radiant energy by materials. The UV-VIS spectrometer is easy to operate and maintain. It may be used in both qualitative and quantitative assessments. Metal and its nanoparticles are commonly measured at wavelengths ranging from 200 to 700 nm. The UV/Vis spectrum can also help us understand the delicate mechanism of complexation between templates, monomers, and cross-linkers during polymerization. It is a rapid, easy, and low-cost characterisation approach. The spectrum may be used to investigate the composition and structure of materials. These findings have applications in academics, business, medical laboratories, and chemical analysis of environmental samples.
IR Spectroscopy
Page: 34-57 (24)
Author: Manisha C. Kotadiya*
DOI: 10.2174/9789815313239124010005
PDF Price: $15
Abstract
Infrared spectroscopy is a method that analyzes the vibrations of atoms in a molecule. An infrared spectrum is generally acquired by sending infrared light through a sample and calculating how much of the incident radiation is absorbed at each energy level. The frequency of vibration of a section of a sample molecule resembles the energy at absorption. The fundamental concepts and terminology of infrared spectroscopy are presented in this chapter. The vibrations of molecules will be examined in this section since they are critical to the understanding of infrared spectra. Various applications of IR spectroscopy are also discussed in brief.
Mass Spectrometry
Page: 58-75 (18)
Author: Manisha C. Kotadiya*
DOI: 10.2174/9789815313239124010006
PDF Price: $15
Abstract
Mass spectrometry is the most effective method for determining molecular structure. It typically offers information on a substance's molecular weight, but it may also show atomic mass units and up to ten-hundredths of atomic mass units depending on the mass analyzer's accuracy. Furthermore, it offers information on the ions (positive charged) created in between the ionization process, related to the molecule's chemical structure and the type of bonds. During these years, the technique paired with the use of software and databases, has been spectacular, enhancing ionization processes and ion analysis. This chapter will demonstrate how mass spectrometry has aided in quality control analysis.
A Brief Account on Recent Advancements and Applications of NMR Spectroscopy
Page: 76-88 (13)
Author: Tejas M. Dhameliya*, Priyansh Rastogi, Hely S. Shah, Prit D. Savaliya, Vidhisha N. Savaliya and Kinalkumar P. Shah
DOI: 10.2174/9789815313239124010007
PDF Price: $15
Abstract
The present book chapter has highlighted the various types of NMR spectroscopy, including solid-state NMR, solution-state NMR, and their applications in hybridization with other spectroscopic techniques in pharmaceutical analysis, drug discovery, and impurity profiling. NMR has been a powerful tool for both drug discovery and the study of the structure and dynamics of biomolecules in conjunction with X-ray crystallography. Along with other chemometric techniques like principal component analysis, discriminant analysis, and partial least square regression are used. In the pharmaceutical sector, NMR has been found to be much important in determining the purity of medications with their various variants, the validity of herbal products/heparin, fingerprinting of isotopes, etc.
Raman Spectroscopy
Page: 89-102 (14)
Author: Manisha C. Kotadiya*
DOI: 10.2174/9789815313239124010008
PDF Price: $15
Abstract
Raman spectroscopy is a type of spectroscopy that is used to detect vibrational, rotational, and other low-frequency modes in a system. It is based on the Raman scattering (inelasticity) of monochromatic light. When laser light interacts with molecular vibrations, the energy of the laser photons is moved up or down. The energy shift reveals information about the system's vibrational modes. This chapter defines Raman spectroscopy, and its various varieties, and explains some of its most important and advanced uses.
Introduction
Organic Spectroscopy: Technology and Applications is an essential guide to the principles and practices of spectroscopy in organic chemistry. This comprehensive text covers the fundamentals of the electromagnetic spectrum, UV-visible, infrared (IR), Raman, nuclear magnetic resonance (NMR), and mass spectrometry, providing a structured approach to understanding each technique`s role in molecular analysis. Designed for students and professionals alike, the book emphasizes problem-solving and structural analysis, offering a methodical progression through each technique to build practical expertise. Illustrated with detailed diagrams and real-world spectra, the text also includes solved examples to reinforce learning and enhance application skills. Key Features: - Comprehensive coverage of core spectroscopy techniques: UV-visible, IR, Raman, NMR, and mass spectrometry. - Step-by-step explanations and problem-solving techniques for structural analysis. - Numerous illustrations and spectra for visual learning.