Preface
Page: ii-ii (1)
Author: Jayalakshmi Krishnan, Sigamani Panneer, P. Thiyagarajan, Balachandar Vellingiri and Pradeep Kumar Srivastava
DOI: 10.2174/9798898812768125010002
Climate Change and Vector-Borne Diseases in General
Page: 1-20 (20)
Author: Rajalakshmi Anbalagan and Jayalakshmi Krishnan*
DOI: 10.2174/9798898812768125010004
PDF Price: $30
Abstract
Many arthropod species, including ticks, fleas, sand flies, mosquitoes, triatomine bugs, and black flies, serve as vectors for numerous diseases that affect humans and animals. These vectors transmit pathogens such as bacteria, viruses, and protozoa, which cause diseases like dengue fever, West Nile Virus, Lyme disease, and malaria. As cold-blooded animals, arthropod vectors are highly sensitive to fluctuations in climatic factors. Climate change significantly impacts several aspects of vector biology and ecology, including survival and reproduction, abundance and distribution, pathogen development and survival, as well as spatiotemporal distribution. Generally, climate change is a crucial factor influencing the survival, reproduction, distribution, and density of disease vectors, subsequently affecting the epidemiology of vector-borne diseases.
Climate Change and Scrub Typhus
Page: 21-47 (27)
Author: S. K. Farhat and Jayalakshmi Krishnan*
DOI: 10.2174/9798898812768125010005
PDF Price: $30
Abstract
Vector-borne diseases are infections transmitted to humans through the bite of vectors, which are transmitted by arthropods such as mosquitoes, ticks, fleas, and mites. These zoonoses have become a major public health alarm affecting millions of people globally. According to recent reports from the World Health Organization (WHO), the estimated number of cases of vector-borne diseases, namely malaria and Dengue, was 247 million and 390 million, respectively, with cases reported globally. The change in environmental conditions like climate change with variations in the temperature, humidity, rainfall, and precipitation has impacted the change in disease dynamics. This chapter explores the relationship between the impact of climate change and Scrub typhus as well as the risk factors that contribute to Scrub typhus and climate change.
Climate Change and Kyasanur Forest Disease (KFD)
Page: 48-93 (46)
Author: Sathya Jeevitha Balakrishnan and Jayalakshmi Krishnan*
DOI: 10.2174/9798898812768125010006
PDF Price: $30
Abstract
Climate change is significantly impacting the epidemiology of Kyasanur Forest Disease [KFD], a viral tick-borne hemorrhagic fever indigenous to India's Western Ghats area. Alterations in temperature and precipitation patterns directly affect the survival, development, and activity of Haemaphysalis spinigera, the primary vector for KFDV, as well as the distribution and behavior of animal hosts. Warmer and more humid conditions, driven by climate change, create favorable environments for tick proliferation, potentially expanding their geographical range and increasing human-tick interactions. Deforestation and habitat fragmentation also exacerbate the situation by disrupting the balance between vectors, hosts, and humans. This environmental degradation forces animal reservoirs, such as monkeys, and human populations into closer touch, heightening the risk of virus transmission. Seasonal variations play a crucial role, with KFD incidence peaking during the drier, hotter months when tick activity is at its highest. The annual transmission cycle in regions like Shivamogga district shows cases emerging in January, peaking in March, and declining by June, with a resurgence in November, demonstrating a clear link between climate patterns and disease spread. Understanding the intricate relationship between climate change, tick ecology, and KFD transmission is essential for developing effective public health strategies and alleviating future outbreaks. This chapter underscores the urgent need for integrated approaches to address the complex interplay of environmental changes and disease dynamics.
Climate Change and Dengue: A Growing Threat
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Author: S Binduja and Jayalakshmi Krishnan*
DOI: 10.2174/9798898812768125010007
PDF Price: $30
Abstract
Climate change is a significant driver of shifts in the distribution and prevalence of vector-borne diseases, with dengue fever being a prominent example. Dengue, caused by the dengue virus and transmitted primarily by Aedes aegypti and Aedes albopictus mosquitoes, has seen a marked increase in incidence and geographic spread in recent decades. This chapter explores the multifaceted relationship between climate change and dengue transmission, highlighting how rising temperatures, altered rainfall patterns, and increased humidity contribute to mosquito proliferation and viral transmission.
Climate Change and Malaria
Page: 126-160 (35)
Author: Joel Jaison and Jayalakshmi Krishnan*
DOI: 10.2174/9798898812768125010008
PDF Price: $30
Abstract
This chapter discusses the complex relationship between climate change and malaria, highlighting the deep impact of environmental shifts on vector-borne diseases. It begins by exploring the broader context of climate change and its influence on the distribution and intensity of vector-borne diseases globally. A key focus is on the impact of changing climate patterns on Anopheles mosquitoes, the primary vectors of malaria. The chapter examines how temperature, precipitation, and humidity variations affect mosquito behaviour, life cycle, and habitat suitability, consequently altering malaria transmission dynamics. The economic implications of these changes are analysed, emphasising the burden on healthcare systems and economies, particularly in vulnerable regions. The chapter also discusses the role of climate control and mitigation strategies in managing the spread of malaria. It outlines various interventions to reduce greenhouse gas emissions and improve adaptive capacities to mitigate the adverse effects of climate change on malaria prevalence. Disease surveillance is seen as a crucial component in this context, with an emphasis on the need for monitoring systems to track changes in disease patterns and vector populations. Innovative approaches and technologies for surveillance and data collection are presented, highlighting their importance in early detection and response to malaria outbreaks. This chapter provides current research and case studies and an overview of the challenges and opportunities in addressing the drastic effects of climate change and malaria. It emphasises the importance of integrated vector management strategies combining climate action with public health initiatives to reduce the spread of malaria.
Climate Change and Crimean-Congo Hemorrhagic Fever (CCHF)
Page: 161-191 (31)
Author: R Narendar and Jayalakshmi Krishnan*
DOI: 10.2174/9798898812768125010009
PDF Price: $30
Abstract
Crimean-Congo Hemorrhagic Fever (CCHF) is a highly virulent viral disease characterized by a rapid onset of symptoms and significant mortality rates. The primary mode of transmission to humans is through tick bites, particularly from the Hyalomma genus, or through direct contact with infected animals or humans. Clinically, CCHF typically begins with the abrupt onset of fever, myalgia, headache, nausea, vomiting, and diarrhea. As the disease advances, patients may exhibit severe hemorrhagic manifestations, including extensive bruising, epistaxis, and uncontrolled bleeding from venipuncture sites. The progression can result in multi-organ failure, with a fatality rate of up to 40%. CCHF is endemic in regions of Africa, Asia, Eastern Europe, and the Mediterranean. Recent decades have seen an expansion of its geographic range, attributed to factors such as climate change and increased global movement. Populations at elevated risk include healthcare workers and individuals involved in livestock handling and meat processing. Currently, the management of CCHF is primarily supportive, as there are no specific antiviral treatments approved for this disease. Key preventive measures include avoiding tick bites, adhering to safe practices during meat processing, and using personal protective equipment properly. Continuous surveillance, ongoing research, and robust public health preparedness are crucial to address this escalating global health threat effectively.
Subject Index
Page: 192-195 (4)
Author: Jayalakshmi Krishnan, Sigamani Panneer, P. Thiyagarajan, Balachandar Vellingiri and Pradeep Kumar Srivastava
DOI: 10.2174/9798898812768125010010
Introduction
A clear and timely overview of how global climate shifts are reshaping the spread, intensity, and impact of major vector-borne diseases.The Changing Trends of Vector-Borne Diseases to Climate Change explains how rising temperatures, changing rainfall patterns, humidity levels, and global movement accelerate mosquito and tick proliferation, expand endemic zones, and increase disease severity. Focusing on dengue and Crimean-Congo Hemorrhagic Fever (CCHF), it also highlights clinical features, transmission pathways, prevention strategies, and the urgent need for surveillance and preparedness. Key Features: - Explains how climate variables drive the spread of vector-borne diseases. - Highlights major case studies, including dengue and CCHF. - Describes transmission pathways, clinical progression, and public-health risks. - Emphasizes prevention, surveillance, and global health preparedness.

