Search Result "Drug metabolite safety assessment"

Research Article

Mixed Matrix Method Provides A Reliable Metabolite Exposure Comparison for Assessment of Metabolites in Safety Testing (MIST)

Journal: Drug Metabolism Letters
Volume: 11 Issue: 1 Year: 2017 Page: 21-28
Author(s): Ryan H. Takahashi,Cyrus Khojasteh,Matthew Wright,Cornelis E.C.A. Hop,Shuguang Ma

Addressing MIST (Metabolites in Safety Testing): Bioanalytical Approaches to Address Metabolite Exposures in Humans and Animals

Journal: Current Drug Metabolism
Volume: 12 Issue: 6 Year: 2011 Page: 578-586
Author(s): Hongying Gao, R. Scott Obach

On Mechanisms of Reactive Metabolite Formation from Drugs

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 13 Issue: 5 Year: 2013 Page: 720-729
Author(s): Alf Claesson, Ola Spjuth

Are Circulating Metabolites Important in Pharmacokinetic Drug-Drug Interactions? A Retroanalysis of Clinical Data

Journal: Current Drug Metabolism
Volume: 15 Issue: 8 Year: 2014 Page: 767-790
Author(s): Yuan-Sheng Zhao,Feng Chen,Li Li

Enantioselective Analysis of Antimalarial Drugs and their Metabolites

Journal: Current Pharmaceutical Analysis
Volume: 6 Issue: 1 Year: 2010 Page: 15-29
Author(s): Igor R. Santos Magalhaes, Pierina S. Bonato

The In Silico Prediction of Human-Specific Metabolites from Hepatotoxic Drugs

Journal: Current Drug Discovery Technologies
Volume: 7 Issue: 3 Year: 2010 Page: 170-187
Author(s): Ravouru Nagaraju, Ande Penchala Prathusha, Rajesh Kaza, Koganti Bharathi, Luis G. Valerio, Anthony Long

Application of Mass Spectrometry for Metabolite Identification

Journal: Current Drug Metabolism
Volume: 7 Issue: 5 Year: 2006 Page: 503-523
Author(s): Shuguang Ma, Swapan K. Chowdhury, Kevin B. Alton

Review Article

Endogenous Biomarkers to Assess Drug-Drug Interactions by Drug Transporters and Enzymes

Journal: Current Drug Metabolism
Volume: 18 Issue: 8 Year: 2017 Page: 757-768
Author(s): T. Thanga Mariappan,Hong Shen,Punit Marathe

Are Chemically Reactive Metabolites Responsible for Adverse Reactions to Drugs?

Journal: Current Drug Metabolism
Volume: 3 Issue: 4 Year: 2002 Page: 351-366
Author(s): D. P. Williams, N. R. Kitteringham, D. J. Naisbitt, M. Pirmohamed, D. A. Smith, B. K. Park

Investigating Drug-induced Mitochondrial Toxicity: A Biosensor to Increase Drug Safety?

Journal: Current Drug Safety
Volume: 4 Issue: 1 Year: 2009 Page: 34-54
Author(s): Claudia V. Pereira, Ana C. Moreira, Susana P. Pereira, Nuno G. Machado, Filipa S. Carvalho, Vilma A. Sardao, Paulo J. Oliveira

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