Search Result "Nutlins"

Nutlins and Ionizing Radiation in Cancer Therapy

Journal: Current Pharmaceutical Design
Volume: 16 Issue: 1 Year: 2010 Page: 1427-1442
Author(s): Gianna Impicciatore, Silvia Sancilio, Sebastiano Miscia, Roberta Di Pietro

Recent Advances in the Therapeutic Perspectives of Nutlin-3

Journal: Current Pharmaceutical Design
Volume: 17 Issue: 6 Year: 2011 Page: 569-577
Author(s): Paola Secchiero, Raffaella Bosco, Claudio Celeghini, Giorgio Zauli

Exposure of B Cell Chronic Lymphocytic Leukemia (B-CLL) Cells to Nutlin-3 Induces a Characteristic Gene Expression Profile, which Correlates with Nutlin-3-Mediated Cytotoxicity (Supplementry Table)

Journal: Current Cancer Drug Targets
Volume: 9 Issue: 4 Year: 2009 Page: 510-518
Author(s): G. Zauli, M. G. di Iasio, P. Secchiero, M. Dal Bo, D. Marconi, R. Bomben, G. Del Poeta, V. Gattei

The MDM2 Inhibitor Nutlins as an Innovative Therapeutic Tool for the Treatment of Haematological Malignancies

Journal: Current Pharmaceutical Design
Volume: 14 Issue: 2 Year: 2008 Page: 2100-2110
Author(s): Paola Secchiero, Maria Grazia di Iasio, Arianna Gonelli, Giorgio Zauli

Review Article open access plus

Nutlin-3, A p53-Mdm2 Antagonist for Nasopharyngeal Carcinoma Treatment

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 18 Issue: 2 Year: 2018 Page: 173-183
Author(s): Voon Yee-Lin,Wong Pooi-Fong,Alan Khoo Soo-Beng

Synergistic Cytotoxic Activity of Recombinant TRAIL Plus the Non-Genotoxic Activator of the p53 Pathway Nutlin-3 in Acute Myeloid Leukemia Cells

Journal: Current Drug Metabolism
Volume: 8 Issue: 4 Year: 2007 Page: 395-403
Author(s): Paola Secchiero, Carlotta Zerbinati, Maria Grazia di Iasio, Elisabetta Melloni, Mario Tiribelli, Vittorio Grill, Giorgio Zauli

Nanoparticles Loaded with Nutlin-3 Display Cytotoxicity Towards p53wildtype JVM-2 But Not Towards p53mutated BJAB Leukemic Cells

Journal: Current Medicinal Chemistry
Volume: 20 Issue: 2 Year: 2013 Page: 2712-2722
Author(s): R. Voltan, P. Secchiero, B. Ruozi, L. Caruso, F. Forni, M. Palomba, G. Zauli, M.A. Vandelli

Pharmacologic Activation of p53 by Small-Molecule MDM2 Antagonists

Journal: Current Pharmaceutical Design
Volume: 17 Issue: 6 Year: 2011 Page: 560-568
Author(s): Hong Shen, Carl G. Maki

Targeting MDM2 and MDMX in Retinoblastoma

Journal: Current Cancer Drug Targets
Volume: 7 Issue: 7 Year: 2007 Page: 689-695
Author(s): Nikia A. Laurie, Chie Schin-Shih, Michael A. Dyer

MDM2-p53 Interaction in Paediatric Solid Tumours: Preclinical Rationale, Biomarkers and Resistance

Journal: Current Drug Targets
Volume: 15 Issue: 1 Year: 2014 Page: 114-123
Author(s): Giuseppe Barone,Deborah A. Tweddle,Jason M. Shohet,Louis Chesler,Lucas Moreno,Andrew DJ Pearson,Tom Van Maerken

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