Search Result "PIM-1 kinase"

Research Article

Identification of Pim-1 Kinase Inhibitors by Pharmacophore Model, MolecularDocking-based Virtual Screening, and Biological Evaluation

Journal: Current Computer-Aided Drug Design
Volume: 18 Issue: 3 Year: 2022 Page: 240-246

Research Article

Heterocyclization of Thiophenes Derived from Estrone Followed by Cytotoxic, HTRF Kinase and Pim-1 Kinase Evaluations

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 18 Issue: 1 Year: 2018 Page: 1711-1728
Author(s): Mahmoud A. Abdelaziz Mahmoud,Rafat Milad Mohareb,Mashari A. Al-Sharif

New Potent and Selective Inhibitor of Pim-1/3 Protein Kinases Sensitizes Human Colon Carcinoma Cells to Doxorubicin

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 14 Issue: 9 Year: 2014 Page: 1228-1236
Author(s): Pascale Moreau,Lyubov G. Dezhenkova,Fabrice Anizon,Lionel Nauton,Vincent Thery,Shuguang Liang,Dmitry N. Kaluzhny,Alexander A. Shtil

Research Article

New Mechanistic Insight on the PIM-1 Kinase Inhibitor AZD1208 Using Multidrug Resistant Human Erythroleukemia Cell Lines and Molecular Docking Simulations

Journal: Current Topics in Medicinal Chemistry
Volume: 19 Issue: 1 Year: 2019 Page: 914-926
Author(s): Maiara Bernardes Marques,Michael González-Durruthy,Bruna Félix da Silva Nornberg,Bruno Rodrigues Oliveira,Daniela Volcan Almeida,Ana Paula de Souza Votto,Luis Fernando Marins

Review Article

Signal Transduction through JAK-STAT and NF-κB Regulated Pim-1 Kinase: Novel Target for Anticancer Leads

Journal: Current Signal Transduction Therapy
Volume: 13 Issue: 2 Year: 2018 Page: 83-104
Author(s): Sisir Nandi,Mohd Salman,Ankita Sharma,Mohit Kumar

The Pim Kinases: New Targets for Drug Development

Journal: Current Drug Targets
Volume: 12 Issue: 1 Year: 2011 Page: 2059-2066
Author(s): Ronan Swords, Kevin Kelly, Jennifer Carew, Stefan Nawrocki, Devalingam Mahalingam, John Sarantopoulos, David Bearss, Francis Giles

Research Article

The Uses of Dimedone for the Synthesis of Thiophene, Thiazole and Annulated Derivatives with Antitumor, Pim-1 Kinase Inhibitions, PAINS Evaluations and Molecular Docking

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 21 Issue: 0 Year: 2021 Page: 1-20
Author(s): Wagnat W. Wardakhan,Amira M. Elmetwally,Abeer A. Mohamed,Rafat M. Mohareb

Research Article

Synthesis of Tetrahydrobenzo[b]thiophene-3-carbohydrazide Derivatives as Potential Anti-cancer Agents and Pim-1 Kinase Inhibitors

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 19 Issue: 1 Year: 2019 Page: 1737-1753
Author(s): Rafat Milad Mohareb,Wagnat Wahba Wardakhan,Nermeen Saeed Abbas

Density Functional Theory, Docking, Bioisosteric Replacement, Pharmacophore Perception, Physical Chemical Analyses of the Interactions of Novel PIM-1 Inhibitors with Suitable Pharmacokinetic Properties for Cancer Treatment

Journal: Current Physical Chemistry
Volume: 3 Issue: 4 Year: 2013 Page: 408-412
Author(s): Luiz R. G. Filho,Gustavo Y. Miyake,Carlos H. T. P. da Silva

Research Article

New Approaches for the Synthesis of Heterocyclic Compounds Corporating Benzo[d]imidazole as Anticancer Agents, Tyrosine, Pim-1 Kinases Inhibitions and their PAINS Evaluations

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 21 Issue: 3 Year: 2021 Page: 279-294
Author(s): Rafat M. Mohareb,Yara R. Milad,Bahaa M. Mostafa,Reem A. El-Ansary

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