Search Result "Presenilin"


Physiological Functions of Presenilins; Beyond γ-Secretase

Journal: Current Pharmaceutical Biotechnology
Volume: 15 Issue: 1 Year: 2014 Page: 1019-1025
Author(s): Ibolya Stiller, Beata Lizak, Gabor Banhegyi

The Catalytic Core of γ-Secretase: Presenilin Revisited

Journal: Current Alzheimer Research
Volume: 5 Issue: 2 Year: 2008 Page: 147-157
Author(s): Harald Steiner

Recent Insights on the Pro-Apoptotic Phenotype Elicited by Presenilin 2 and its Caspase and Presenilinase-Derived Fragments

Journal: Current Alzheimer Research
Volume: 2 Issue: 5 Year: 2005 Page: 507-514
Author(s): Cristine A da Costa

Changes in the Expression of the Alzheimers Disease-Associated Presenilin Gene in Drosophila Heart Leads to Cardiac Dysfunction

Journal: Current Alzheimer Research
Volume: 8 Issue: 3 Year: 2011 Page: 313-322
Author(s): A. Li, C. Zhou, J. Moore, P. Zhang, T.-H. Tsai, H.-C. Lee, D. M. Romano, M. L.McKee, D. A. Schoenfeld, M. J. Serra, K. Raygor, H. F. Cantiello, J. G. Fujimoto, R. E. Tanzi

Presenilin and γ -Secretase Activity: A Viable Therapeutic Target for Alzheimers Disease?

Journal: Current Signal Transduction Therapy
Volume: 5 Issue: 2 Year: 2010 Page: 128-140
Author(s): Run Yan, Justin V. McCarthy

Research Article

Presenilin 1 and APP Gene Mutations in Early-Onset AD Families from a Southeast Region of China

Journal: Current Alzheimer Research
Volume: 17 Issue: 6 Year: 2020 Page: 540-546
Author(s): Jiajia Zhou,Yi Chen,Fanxia Meng,Kan Zhang,Xiaoyan Liu,Guoping Peng

Familial Alzheimers Disease Mutations in Presenilin 1 Do Not Alter Levels of the Secreted Amyloid-β Protein Precursor Generated by β-Secretase Cleavage

Journal: Current Alzheimer Research
Volume: 7 Issue: 1 Year: 2010 Page: 21-26
Author(s): C. Zhang, A. Browne, D. Y. Kim, R. E. Tanzi

Research Article

Asymptomatic Carriers of Presenilin-1 E318G Variant Show no Cerebrospinal Fluid Biochemical Signs Suggestive of Alzheimer’s disease in a Family with Late-onset Dementia

Journal: Current Alzheimer Research
Volume: 16 Issue: 1 Year: 2019 Page: 1-7
Author(s): Vladimiro Artuso,Luisa Benussi,Roberta Ghidoni,Soraya Moradi-Bachiller,Federica Fusco,Stefano Curtolo,Ignazio Roiter,Gianluigi Forloni,Diego Albani

γ-Secretase as a Target for Alzheimers Disease

Journal: Current Topics in Medicinal Chemistry
Volume: 2 Issue: 4 Year: 2002 Page: 371-383
Author(s): Michael S. Wolf

The γ /η-Secretase-Derived APP Intracellular Domain Fragments Regulate p53

Journal: Current Alzheimer Research
Volume: 4 Issue: 4 Year: 2007 Page: 423-426
Author(s): Frederic Checler, Claire Sunyach, Raphaelle Pardossi-Piquard, Jean Sevalle, Bruno Vincent, Toshitaka Kawarai, Nadege Girardot, Peter St George-Hyslop, Cristine Alves da Costa

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