Search Result "Alanine-scanning mutagenesis"


Research Article

Designing Novel Teduglutide Analogues with Improved Binding Affinity: An In Silico Peptide Engineering Approach

Journal: Current Computer-Aided Drug Design
Volume: 17 Issue: 2 Year: 2021 Page: 225-234
Author(s): Ali A. Alizadeh,Siavoush Dastmalchi

Research Article

Mechanistic Insights to the Binding of Antibody CR3022 Against RBD from SARS-CoV and HCoV-19/SARS-CoV-2: A Computational Study

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 24 Issue: 7 Year: 2021 Page: 1069-1082
Author(s): Wei Yu,Xiaomin Wu,Jiayi Ren,Xiaochun Zhang,Yueming Wang,Chengming Li,Wenwen Xu,Jason Li,Gang Li,Weihong Zheng,Huaxin Liao,Xiaohui Yuan

Review Article

Monoclonal Antibodies Against Infectious Microbes: too little too late!

Journal: Infectious Disorders - Drug Targets
Volume: 21 Issue: 1 Year: 2021 Page: 4-27
Author(s): Gerard M. Raj,Rekha Priyadarshini,Sakthibalan Murugesan,Mangaiarkkarasi Adhimoolam

Current Frontiers

Development of Allosteric Modulators of Voltage-Gated Na+ Channels: A Novel Approach for an Old Target

Journal: Current Topics in Medicinal Chemistry
Volume: 21 Issue: 1 Year: 2021 Page: 841-848
Author(s): Nolan M. Dvorak,Paul A. Wadsworth,Pingyuan Wang,Jia Zhou,Fernanda Laezza

Review Article

DHODH Hot Spots: An Underexplored Source to Guide Drug Development Efforts

Journal: Current Topics in Medicinal Chemistry
Volume: 21 Issue: 0 Year: 2021 Page: 1-21
Author(s): Thamires Quadros Froes,Luana Carlos Campisano Zapata,Juliana Sayuri Akamine,Marcelo Santos Castilho,Maria Cristina Nonato

Review Article

An Overview of 7α- and 7β-Hydroxysteroid Dehydrogenases: Structure, Specificity and Practical Application

Journal: Protein & Peptide Letters
Volume: 28 Issue: 0 Year: 2021 Page: 1-14
Author(s): Deshuai Lou,Xi Liu,Jun Tan

Review Article

Synaptotagmin-1: A Multi-Functional Protein that Mediates Vesicle Docking, Priming, and Fusion

Journal: Current Protein & Peptide Science
Volume: 22 Issue: 0 Year: 2021 Page: 1-9
Author(s): Najeeb Ullah,Ezzouhra El Maaiden,Md. Sahab Uddin,Ghulam Md Ashraf

Pradimicin and Benanomicin Antibiotics: From Antifungal Polyketide Natural Products to Antiviral Agents with a Unique Carbohydrate- Binding Mode of Action

Ebook: Frontiers in Natural Product Chemistry

Volume: 7 Year: 2021
Author(s): Rocío Abín,Visitación López-Miranda,Ana San-Félix,Ernesto Quesada
Doi: 10.2174/97816810891641210701
General Review Article

Anti-cancer Immunotoxins, Challenges, and Approaches

Journal: Current Pharmaceutical Design
Volume: 27 Issue: 7 Year: 2021 Page: 932-941
Author(s): Maryam Dashtiahangar,Leila Rahbarnia,Safar Farajnia,Arash Salmaninejad,Arezoo Gowhari Shabgah,Samaneh Ghasemali

Research Article

Antagonistic Effect of Truncated Fragments of Bacillus thuringiensis Vip3Aa on the Larvicidal Activity of its Full-length Protein

Journal: Protein & Peptide Letters
Volume: 28 Issue: 2 Year: 2021 Page: 11-19
Author(s): Patcharaporn Boonyos,Chutchanun Trakulnalueamsai,Amporn Rungrod,Sukumal Chongthammakun,Boonhiang Promdonkoy

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